Straightforward Syntheses of the Three Possible Isomers of (±)-2-[3-(Hydroxybenzoyl) phenyl]propanoic Acid, Metabolites of (±)-Ketoprofen

Thallium(III) in Organic Synthesis

“…In recent years, several papers dealing with the conversion of alkyl aryl ketones into the corresponding carboxylic acids or esters have been published. [27][28][29][30][31][32][33] Illustrative examples are given in Scheme 6. The most common conditions involve the use of TTN in MeOH/TMOF (trimethylorthoformate) or in MeOH/HClO 4 .…”