STR genetic diversity in a Mediterranean population from the south of the Iberian Peninsula

Abstract

Sixteen Y-chromosomal short tandem repeats (STRs) (DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS385, DYS437, DYS438, DYS439, DYS448, DYS456, DYS458, DYS635 and GATA H4.1) were typed in DNA samples from 52 unrelated men and 15 autosomal STRs (CSF1PO, D2S1338, D3S1358, D5S818, D7S820, D8S1179, D13S317, D16S539, D18S51, D19S433, D21S11, FGA, TH01, TPOX, vWA) were also studied for a group of 90 individuals (men and women) from the same population (Andalusians from La Alpujarra, South of Spain). The Alpujarrenian population represents an example of an isolated population with remarkable geographical, cultural and historical characteristics. High haplotype diversities were observed for the studied polymorphisms, 0.98 and 1 for YSTRs and autosomal STRs, respectively. Population comparisons for the autosomal STR allele distributions revealed remarkable levels of global homogeneity among samples geographically related.

Y-STR variation in the Basque diaspora in the Western USA: evolutionary and forensic perspectives

“…With this aim, we present here the first study of 17 Y-STR loci in autochthonous European Basques and the Basque diaspora in the Western USA. [15]; CA-US Caucasian Americans [13]; HI-US Hispanic Americans [13]; AS-US Asian Americans [13]; AF-US African Americans [13]; POR Portugal [16]; ITA Italy [17]; AUS Austria [18]; GER Germany [19]; POL Poland [19]; ROM Romania [20]; GRE Greece [21]; SER Serbia [22]; CRO Croatia [23] Our results demonstrate a very high-level of conservation of the Y chromosome haplotypes characteristic of the European autochthonous Basque population among individuals of the Basque diaspora in the Western USA. No signs of founder haplotypes have been found, probably because the number of European Basque male individuals who have settled in the Western USA has been large enough for a similar Y-haplotype frequency distribution to be reached between the source and the emigrant populations.…”

“…Finally, genetic distance calculations based on the Fst statistic were performed to assess the genetic relationships between the Basque founder population, its Western USA diaspora and other populations from North America and Europe [13,[15][16][17][18][19][20][21][22][23]. Only the populations with the same 17 Y-STR loci data were included in these calculations.…”

Immunoglobulin genes in Andalusia (Spain). Genetic diversity in the Mediterranean space

“…Serum fraction was used for genetic analysis of immunoglobulin allotypes: G1 M (1, 2, 3, 17), G2 M (23), and G3 M (5,6,10,11,13,14,15,16,21,24,28). In parallel, these samples were analysed for KM allotype (1).…”

“…A number of genetic studies have been published on Andalusian population based on blood group system polymorphisms [20], erythrocyte enzymes [21], leucocyte polymorphisms (HLA class II) [22,23], and DNA autosomal and uniparental markers [24][25][26][27][28][29][30]. These surveys show heterogeneous results on the genetic affinity between Andalusia and North Africa -neighbouring western populations specifically.…”

The Y-STR Genetic Diversity of an Idaho Basque Population, with Comparison to European Basques and US Caucasians

“…The power of discrimination (PD) was calculated as the number of different haplotypes divided by the sample size (García et al 2006). An analysis of molecular variance (AMOVA) with 10,000 permutations using ARLEQUIN was performed to generate R ST (Gaibar et al 2010), Barcelona (Sánchez et al 2007), N. Portugal (Pontes et al 2007), Italy (Turrina et al 2006), N. Greece (Leda et al 2009), Serbia (Veselinovic et al 2008), Romania (Stanciu et al 2010), and Algeria (Robino et al 2008).…”