Stoichiometry of long noncoding RNA interactions with other RNAs: Insights from OIP5‐AS1
Jen‐Hao Yang,
Dimitrios Tsitsipatis,
Myriam Gorospe
Abstract:Long noncoding (lnc)RNAs modulate gene expression programs in a range of developmental processes in different organs. In skeletal muscle, lncRNAs have been implicated in myogenesis, the process whereby muscle precursor cells form muscle fibers during embryonic development and regenerate muscle fibers in the adult. Here, we discuss OIP5‐AS1, a lncRNA that is highly expressed in skeletal muscle and is capable of coordinating protein expression programs during myogenesis. Given that several myogenic functions of … Show more
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