Stoffwechsel

Tannenberg,; Mühlbock,; Falkenhausen,; Hüssy, Paul; Knipping, H. W.

doi:10.1007/bf01621118

Cited by 1 publication

(2 citation statements)

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“…The skin is a protective organ continually subject to slight traumata and to local infections. Cohnheim (16) noted that leukocytes get out much sooner and easier from venules than from capillaries; and Tannenberg (17), extending the observation, has reported that when these cells become attached to the capillary wall, as a first step toward emigration, they are buffeted by the swift current and frequently dislodged and whirled away. This does not happen in the venules, which provide ideal conditions for emigration.…”

Section: Discussionmentioning

confidence: 98%

“…Diapedesis under pressure occurs first from the venules (16), and ecchymosis from these vessels is far more frequent than is generally recognized (19). Under circumstances of venous obstruction Tannenberg observed diapedesis taking place from the venules, then from the venous end of the capillaries, and only later from the arterial portion of these latter, despite the fact that through them the pressure was transmitted that was responsible for the lesions (17).…”

Section: Discussionmentioning

confidence: 99%

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The Gradient of Vascular Permeability

Smith

Rous

1931

Journal of Experimental Medicine

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The recognition that permeability increases progressively along the capillaries of voluntary muscle (1) has led us to study the state of affairs in other organs. An exceedingly pronounced gradient is demonstrable in the skin of the frog, and the small cutaneous venules are even more permeable than the adjoining portion of the capillaries (2). Because of the importance of mammalian skin in water storage and regulation, we have proceeded to study this organ. The skin of the albino mouse was chosen for the purpose because the spread of dyes from the blood can be followed with special ease in it. The Escape of Dyes from the Blood into the Skin of the BodyIn preliminary tests vital dyes of known diffusibility were injected into a tail vein of unanesthetized animals which were decapitated shortly after. The skin was found to color evenly with rapidly diffusible pigments, whereas with poorly diffusible ones, such as are especially suited to disclose local differences in vascular permeability, there was to be seen a deep staining of the tissue through which the small venules coursed, before any general coloration of the corium had taken place. The phenomenon was visible only when a skin flap was studied from its under side and even then ordinarily the subcutaneous fat prevented a clear view. To do away with it mice were kept on a reduced ration until they had become thin. They yielded pictures that were highly informative.

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Section: Discussionmentioning

confidence: 98%

Section: Discussionmentioning

confidence: 99%