Stoffenmanager Nano Version 1.0: A Web-Based Tool for Risk Prioritization of Airborne Manufactured Nano Objects

Duuren-Stuurman, B. van; Vink, S.R.; Verbist, Koen; Heussen, G.A.H.; Brouwer, D.H.; Kroese, Dinant; Niftrik, Maikel F. J. Van; Tielemans, Erik; Fransman, Wouter

doi:10.1093/annhyg/mer113

Cited by 51 publications

(25 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Currently, there are situations in which CB cannot provide the precision and accuracy necessary to protect worker health; alternatively, there are situations in which the use of CB may recommend a higher level of exposure control than is necessary (Van Duuren-Stuurman et al, 2012). Although CB is not intended to be a replacement for traditional exposure monitoring and the use of OELs, it can be an integral part of a tiered risk management strategy for controlling worker exposures to ENMs.…”

Section: Discussionmentioning

confidence: 99%

“…A number of CB strategies have been proposed for use in workplaces where exposure to ENMs may occur. These nanomaterial specific strategies include, CB Nanotool, Precautionary Matrix, the French Agency for Food, Environmental and Occupational Safety (ANSES), Stoffenmanager ® Nano, NanoSafer (Danish only) and Guidance (Cornelissen, Jongeneelen, & van Broekhuizen, 2011; Groso, Petri-Fink, Magrez, Riediker, & Meyer, 2010; Höck et al, 2008; Ostiguy, Riediker, Triolet, Troisfontaines, & Vernez, 2010; Paik et al, 2008; Riediker et al, 2012; Schneider et al, 2011; Van Duuren-Stuurman et al, 2012; D. M. Zalk et al, 2009).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Can control banding be useful for the safe handling of nanomaterials? A systematic review

Eastlake

Zumwalde²,

Geraci

2016

J Nanopart Res

View full text Add to dashboard Cite

Objectives Control banding (CB) is a risk management strategy that has been used to identify and recommend exposure control measures to potentially hazardous substances for which toxicological information is limited. The application of CB and level of expertise required for implementation and management can differ depending on knowledge of the hazard potential, the likelihood of exposure, and the ability to verify the effectiveness of exposure control measures. A number of different strategies have been proposed for using CB in workplaces where exposure to engineered nanomaterials (ENMs) can occur. However, it is unclear if the use of CB can effectively reduce worker exposure to nanomaterials. A systematic review of studies was conducted to answer the question “can control banding be useful to ensure adequate controls for the safe handling of nanomaterials.” Methods A variety of databases were searched to identify relevant studies pertaining to CB. Database search terms included ‘control’, ‘hazard’, ‘exposure’ and ‘risk’ banding as well as the use of these terms in the context of nanotechnology or nanomaterials. Other potentially relevant studies were identified during the review of articles obtained in the systematic review process. Identification of studies and the extraction of data were independently conducted by the reviewers. Quality of the studies was assessed using the Methodological Index for Non-Randomized Studies (MINORS). The quality of the evidence was evaluated using Grading of Recommendations Assessment, Development and Evaluation (GRADE). Results A total of 235 records were identified in the database search in which 70 records were determined to be eligible for full-text review. Only two studies were identified that met the inclusion criteria. These studies evaluated the application of the CB Nanotool in workplaces where ENMs were being handled. A total of 32 different nanomaterial handling activities were evaluated in these studies by comparing the recommended exposure controls using CB to existing exposure controls previously recommended by an industrial hygienist. It was determined that the selection of exposure controls using CB were consistent with those recommended by an industrial hygienist for 19 out of 32 (59.4%) job activities. A higher level of exposure control was recommended for nine out of 32 (28.1%) job activities using CB while four out of 32 (12.5%) job activities had in place exposure controls that were more stringent than those recommended using CB. After evaluation using GRADE, evidence indicated that the use of CB Nanotool can recommend exposure controls for many ENM job activities that would be consistent with those recommended by an experienced industrial hygienist. Conclusion The use of CB for reducing exposures to ENMs has the potential to be an effective risk management strategy when information is limited on the health risk to the nanomaterial and/or there is an absence of an occupational exposure limit (OEL). However, there remains a lack of evidence to conclude...

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Can control banding be useful for the safe handling of nanomaterials? A systematic review

Eastlake

Zumwalde²,

Geraci

2016

J Nanopart Res

View full text Add to dashboard Cite

show abstract

“…The ND emission rates may be used to estimate the increase in ND concentration level if the work is scaled-up and if the work station environmental conditions remain similar [67] and in risk assessment tools, such as, Stoffenmanager Nano [68]. …”

Section: Discussionmentioning

confidence: 99%

Range-Finding Risk Assessment of Inhalation Exposure to Nanodiamonds in a Laboratory Environment

Koivisto

Palomäki

Viitanen

et al. 2014

IJERPH

View full text Add to dashboard Cite

This study considers fundamental methods in occupational risk assessment of exposure to airborne engineered nanomaterials. We discuss characterization of particle emissions, exposure assessment, hazard assessment with in vitro studies, and risk range characterization using calculated inhaled doses and dose-response translated to humans from in vitro studies. Here, the methods were utilized to assess workers’ risk range of inhalation exposure to nanodiamonds (NDs) during handling and sieving of ND powder. NDs were agglomerated to over 500 nm particles, and mean exposure levels of different work tasks varied from 0.24 to 4.96 µg·m−3 (0.08 to 0.74 cm−3). In vitro-experiments suggested that ND exposure may cause a risk for activation of inflammatory cascade. However, risk range characterization based on in vitro dose-response was not performed because accurate assessment of delivered (settled) dose on the cells was not possible. Comparison of ND exposure with common pollutants revealed that ND exposure was below 5 μg·m−3, which is one of the proposed exposure limits for diesel particulate matter, and the workers’ calculated dose of NDs during the measurement day was 74 ng which corresponded to 0.02% of the modeled daily (24 h) dose of submicrometer urban air particles.

show abstract

“…The evaluated frameworks for environmental risk/impact characterization were Life Cycle Analysis (LCA) [38–40], DuPont’s NanoRisk [41], US EPA’s Comprehensive Environmental Assessment (CEA) [42–43], NanoHAZ [44], Nanomaterial risk screening tool (NRST) [45], Engineered Nanoparticles – Review of Health and Environmental Safety: Human health and Ecological Risk Assessment (ENRHES RA) [46], Risk Quantification based on Probabilistic Mass Flow Modeling Analysis (PMFA Risk Assessment) [47], Forecasting of the Impacts of Nanomaterials in the Environment (FINE) based on Bayesian Networks (BN) [48], and Life Cycle Risk Analysis for nanomaterials (Nano LCRA) [49–50]. The assessed frameworks for occupational risk characterization were Risk based classification for occupational exposure control (Risk based OEL) [51], Risk Classification based on an Industry Insurance Protocol (RCIP) [52], CB Nanotool [53] and the Web-Based Tool for Risk Prioritization of Airborne Manufactured Nano Objects (Stoffenmanager Nano) [54]. …”

Section: Methodsmentioning

confidence: 99%

“…(d) The Web-Based Tool for Risk Prioritization of Airborne Manufactured Nano Objects (“Stoffenmanager Nano”) [54] is a framework based on control banding, similar to the CB Nanotool. The Stoffenmanager Nano approach aims at identifying control measures to reduce the likelihood of inhalation exposure in occupational settings.…”

Section: Reviewmentioning

confidence: 99%

Needs and challenges for assessing the environmental impacts of engineered nanomaterials (ENMs)

Romero-Franco

Godwin

Bilal

et al. 2017

Beilstein J. Nanotechnol.

View full text Add to dashboard Cite

The potential environmental impact of nanomaterials is a critical concern and the ability to assess these potential impacts is top priority for the progress of sustainable nanotechnology. Risk assessment tools are needed to enable decision makers to rapidly assess the potential risks that may be imposed by engineered nanomaterials (ENMs), particularly when confronted by the reality of limited hazard or exposure data. In this review, we examine a range of available risk assessment frameworks considering the contexts in which different stakeholders may need to assess the potential environmental impacts of ENMs. Assessment frameworks and tools that are suitable for the different decision analysis scenarios are then identified. In addition, we identify the gaps that currently exist between the needs of decision makers, for a range of decision scenarios, and the abilities of present frameworks and tools to meet those needs.

show abstract

Stoffenmanager Nano Version 1.0: A Web-Based Tool for Risk Prioritization of Airborne Manufactured Nano Objects

Cited by 51 publications

References 26 publications

Can control banding be useful for the safe handling of nanomaterials? A systematic review

Can control banding be useful for the safe handling of nanomaterials? A systematic review

Range-Finding Risk Assessment of Inhalation Exposure to Nanodiamonds in a Laboratory Environment

Needs and challenges for assessing the environmental impacts of engineered nanomaterials (ENMs)

Contact Info

Product

Resources

About