“…Privilege of noise-delay modeling techniques in interpreting dynamical prospects of biological systems is illustrated by simulating system (38) with parameter values taken from [31] in which similar study on viral infections are analyzed with Lévy noises.…”
Section: Empirical Supportmentioning
confidence: 99%
“… Fig. 1 For the values of , the dynamics exhibited by (38) for days upon simulating with parameter values as in [31] , for the initial values . Note In any epidemics, the infection rates are expected to increase with increase in the infection transmission rates and simulated results reveal that our model found to comply with the criteria briefed above and Figure 1 evinces it.…”
Section: Empirical Supportmentioning
confidence: 99%
“…Final set of simulations are carried out with parameter values taken from [31] in which analytic studies are based on Lèvy noises in [37] model (a model from which system (2) is formulated) and results viewed in Figure 7 are evident that our system (38) is better fit in showcasing real scenario. Fig.…”
Section: Empirical Supportmentioning
confidence: 99%
“…Many researchers and immunologists have pooled literature with works ever since its inception in pandemic cluster [20] , [21] , [22] , [23] , [24] , [25] , [26] emphasizing various dynamical perspectives of COVID-19 infections with statistical data to foresee progressions of infection dynamics over course of time and efforted to enunciate behavioral characteristics like pattern of infection spread [27] , feasible strategies to restrain epidemic outbreaks [28] , [29] etc at host individual level. Even then, the investigatory results excerpted from those studies are ambiguous pertaining to noise factors viz., variations in seasons, geographical locations, behavioral attitude and genetic variations among host population etc that may stimulate, aggravate or sublime the spread in wider scale and are enigmatic on global accord to curb massive spread as every natural phenomenon is an element of uncertainty and random fluctuations play inevasible role in dynamics of environmental systems [15] , [30] , [31] . However, such encumbrances can be vanquished by executing stochastic probes on internal viral dynamics of SARS-CoV-2 virus to presume dynamical progressions exclusively with precision and expedite feasible control strategies with futuristic perspectives.…”
In disease model systems, random noises and time delay factors play key role in interpreting disease dynamics to comprehend deeper insights into the course of dynamics. An endeavor to forecast intercellular behavioral dynamics of SARS-CoV-2 virus via Infection model with responsive host immune mechanisms forms the crux of this research study. Incorporation of time delay factor into infection transmission rates in noisy system epitomizes spectacular view on internal viral dynamics and stability properties are rigorously analyzed around equilibrium steady states to probe feasible strategies in mitigating rapid spread. Efforts to perceive inocular view on infection dynamics are not limited to theoretical frontiers but are substantiated with empirically simulated outcomes and visualized as graphical upshots. Discussions on numerical investigations emphasized shorter incubation periods and vaccination at pertinent time intervals to restrain massive spread and exhibit total immunity against SARS-CoV-2 infections.
“…Privilege of noise-delay modeling techniques in interpreting dynamical prospects of biological systems is illustrated by simulating system (38) with parameter values taken from [31] in which similar study on viral infections are analyzed with Lévy noises.…”
Section: Empirical Supportmentioning
confidence: 99%
“… Fig. 1 For the values of , the dynamics exhibited by (38) for days upon simulating with parameter values as in [31] , for the initial values . Note In any epidemics, the infection rates are expected to increase with increase in the infection transmission rates and simulated results reveal that our model found to comply with the criteria briefed above and Figure 1 evinces it.…”
Section: Empirical Supportmentioning
confidence: 99%
“…Final set of simulations are carried out with parameter values taken from [31] in which analytic studies are based on Lèvy noises in [37] model (a model from which system (2) is formulated) and results viewed in Figure 7 are evident that our system (38) is better fit in showcasing real scenario. Fig.…”
Section: Empirical Supportmentioning
confidence: 99%
“…Many researchers and immunologists have pooled literature with works ever since its inception in pandemic cluster [20] , [21] , [22] , [23] , [24] , [25] , [26] emphasizing various dynamical perspectives of COVID-19 infections with statistical data to foresee progressions of infection dynamics over course of time and efforted to enunciate behavioral characteristics like pattern of infection spread [27] , feasible strategies to restrain epidemic outbreaks [28] , [29] etc at host individual level. Even then, the investigatory results excerpted from those studies are ambiguous pertaining to noise factors viz., variations in seasons, geographical locations, behavioral attitude and genetic variations among host population etc that may stimulate, aggravate or sublime the spread in wider scale and are enigmatic on global accord to curb massive spread as every natural phenomenon is an element of uncertainty and random fluctuations play inevasible role in dynamics of environmental systems [15] , [30] , [31] . However, such encumbrances can be vanquished by executing stochastic probes on internal viral dynamics of SARS-CoV-2 virus to presume dynamical progressions exclusively with precision and expedite feasible control strategies with futuristic perspectives.…”
In disease model systems, random noises and time delay factors play key role in interpreting disease dynamics to comprehend deeper insights into the course of dynamics. An endeavor to forecast intercellular behavioral dynamics of SARS-CoV-2 virus via Infection model with responsive host immune mechanisms forms the crux of this research study. Incorporation of time delay factor into infection transmission rates in noisy system epitomizes spectacular view on internal viral dynamics and stability properties are rigorously analyzed around equilibrium steady states to probe feasible strategies in mitigating rapid spread. Efforts to perceive inocular view on infection dynamics are not limited to theoretical frontiers but are substantiated with empirically simulated outcomes and visualized as graphical upshots. Discussions on numerical investigations emphasized shorter incubation periods and vaccination at pertinent time intervals to restrain massive spread and exhibit total immunity against SARS-CoV-2 infections.
“…Nevertheless, random environmental factors such as sudden climate changes, humidity, temperature and also random transmission process of the infection have a considerable impact on the spread of infectious diseases [29][30][31]. Taking this natural phenomenon into consideration, several works introduced randomness effects into the deterministic biological model in order to reveal the environmental and natural sudden fluctuations of parameters variables in the differential systems.…”
In this paper, we present a novel SICVS COVID-19 pandemic model incorporating a vaccination strategy and crowding effect. First, we investigate the steady states and proved the local stability of the corresponding deterministic problem. Then we study the proposed stochastic epidemic model; we have considered a random incidence highlighting all the improbable fluctuations that appear in the infection process. Hence, the COVID 19 transmission parameter in the considered model will be stochastically perturbed by the white noise. We show the disease extinction of the pandemic according to the stochastic noise intensity. It was established, in the stochastic study, the existence of a possible extinction of the pandemic even if the base reproduction number is greater than unity. Furthermore we discuss the persistence in mean of the studied infection in terms of the stochastic model parameters. Our numerical simulations confirm the theoretical findings. The proposed model was validated and supported by a comparison, during the second wave of the pandemic in Morocco, between the trajectories of the clinical data of Covid-19 and those which represent our SICVS model. In addition, the impact of vaccination and social distancing strategies on reducing the infection severity were observed.
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