2010
DOI: 10.1002/minf.201000134
|View full text |Cite
|
Sign up to set email alerts
|

Stochastic Proximity Embedding: Methods and Applications

Abstract: Since its inception in 1996, the stochastic proximity embedding (SPE) algorithm and its variants have been applied to a wide range of problems in computational chemistry and biology with notable success. At its core, SPE attempts to generate Euclidean coordinates for a set of points so that they satisfy a prescribed set of geometric constraints. The algorithm's appeal rests on three factors: 1) its conceptual and programmatic simplicity; 2) its superior speed and scaling properties; and 3) its broad applicabil… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1
1
1

Citation Types

0
16
0

Year Published

2011
2011
2019
2019

Publication Types

Select...
7
2

Relationship

1
8

Authors

Journals

citations
Cited by 29 publications
(16 citation statements)
references
References 45 publications
0
16
0
Order By: Relevance
“…To testify the superiority of our method, five common dimensionality reduction tools combined with sparse filtering are adopted to process the gearbox dataset respectively. The five tools are: principal component analysis (PCA) [25], locality preserving projection (LPP) [26], Sammon mapping (SM) [27], linear discriminant analysis (LDA) [28], and stochastic proximity embedding (SPE) [29]. The classification results by the five methods are shown in Fig.…”
Section: Diagnosis Resultsmentioning
confidence: 99%
“…To testify the superiority of our method, five common dimensionality reduction tools combined with sparse filtering are adopted to process the gearbox dataset respectively. The five tools are: principal component analysis (PCA) [25], locality preserving projection (LPP) [26], Sammon mapping (SM) [27], linear discriminant analysis (LDA) [28], and stochastic proximity embedding (SPE) [29]. The classification results by the five methods are shown in Fig.…”
Section: Diagnosis Resultsmentioning
confidence: 99%
“…Here, we present a method for visualizing and interpreting high‐dimensional chemical data, which is complementary to SOM and PCA projection and overcomes some of their disadvantages and limitations. The projection is based on stochastic proximity embedding (SPE) 11. SPE embeds data in a low‐dimensional space in such a way that pairwise distances between compounds are preserved.…”
Section: Results Of Retrospective Virtual Screening Given As Average mentioning
confidence: 99%
“…The method of SPE [70,71] performs optimization of a random initial configuration of the system to minimize the violation of predefined constraints, for example, distances between the points, choosing at each step the constraint to minimize in a stochastic manner instead of dealing with all violations simultaneously. A notable recent application of this method is the mapping of the kinase inhibitor space for its broad profiling [72].…”
Section: Other Dimensionality Reduction Methodsmentioning
confidence: 99%