Stimulus-Responsive Polymers Based on Polypeptoid Skeletons

Abstract

Polypeptoids have attracted a lot of atteSDntion because of their unique structural characteristics and special properties. Polypeptoids have the same main chain structures to polypeptides, making them have low cytotoxicity and excellent biocompatibility. Polypeptoids can also respond to external environmental changes by modifying the configurations of the side chains. The external stimuli can be heat, pH, ions, ultraviolet/visible light and active oxygen or their combinations. This review paper discussed the recent research progress in the field of stimulus-responsive polypeptoids, including the design of new stimulus-responsive polypeptoid structures, controlled actuation factors in response to external stimuli and the application of responsive polypeptoid biomaterials in various biomedical and biological nanotechnology, such as drug delivery, tissue engineering and biosensing.

Methods for Predicting Ethylene/Cyclic Olefin Copolymerization Rates Promoted by Single-Site Metallocene: Kinetics Is the Key

“…These include high cost, the requirement to employ it in large molar excess to pre-catalysts, and the loss of stability during prolonged storage, resulting in loss of activating capabilities and irreproducibility of polymers properties. According to the literature, triisobutylaluminium (TIBA)/borate is an excellent activator of metallocene complexes in the polymerization of olefins [ 25 , 26 , 27 , 28 ].…”

“…There are only a few publications in the literature on the kinetics and mechanism of metallocene-catalyzed olefin co- and ter- polymerization based on active center counts. Furthermore, the contributions of R. Landis [ 25 ], Chen [ 4 ], Fan [ 22 ], Kaminsky [ 26 ], Bochmann [ 27 ], and M. Waymouth [ 5 ] have resulted in significant progress in the establishment of innovative copolymerization metallocene catalysts.…”

Modification of Cellulose Nanocrystals With 2-Carboxyethyl Acrylate in the Presence of Epoxy Resin for Enhancing its Adhesive Properties

“…Presently, researchers focused on environmental issues and on providing an affordable and scalable approach for sustainable development have faced one of the most fundamental challenges (Poaty et al, 2014;Li et al, 2018;Alanis et al, 2019;Ullah et al, 2021a). CNCs are a growing area for nanomaterials research candidates because of their attraction for reinforcing agents and due to their reproducibility, high shear stress, and elastic modulus (Yang et al, 2013;Wu et al, 2020;Fang et al, 2021;Niinivaara et al, 2021). CNCs have a high specific surface energy that tends to aggregate during the manufacturing process, forming larger particles.…”

Self-Assembled Membrane-like Nanomaterials from Sequence-Defined Peptoid Block Copolymers

“…For example, polypeptoids have good solubility, strong resistance to enzymatic hydrolysis, good thermal processing performance and highly controllable chemical structures [ 23 ]. As a new biomimetic material to replace polypeptides, polypeptoids have made rapid progress in both synthesis methods and property studies [ 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 ]. However, only a few groups have explored the construction of membrane-like nanomaterials from polypeptoids.…”