Stimuli-responsive piezoelectricity in electrospun polycaprolactone (PCL)/Polyvinylidene fluoride (PVDF) fibrous scaffolds for bone regeneration

Bagherzadeh, Elham; Sherafat, Z.; Zebarjad, Seyed Mojtaba; Khodaei, Azin; Yavari, Saber Amin

doi:10.1016/j.jmrt.2023.01.007

Cited by 19 publications

(13 citation statements)

References 51 publications

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“…According to bone-related gene expression evaluation results (Figure a), it was concluded that the developed PVDF/collagen/PRP-based biomaterial present higher osteoinductivity when compared to the PVDF/collagen composite, demonstrating a promising bone bioimplant. PVDF was also combined with polycaprolactone (PCL) to create fibrous scaffolds for bone regeneration, demonstrating promotion of human mesenchymal stem cells differentiation into osteoblasts.…”

Section: Applicationsmentioning

confidence: 99%

“…According to bone-related gene expression evaluation results (Figure 43a), it was concluded that the developed PVDF/collagen/PRP-based biomaterial present higher osteoinductivity when compared to the PVDF/collagen composite, demonstrating a promising bone bioimplant. PVDF was also combined with polycaprolactone (PCL) to create fibrous scaffolds for bone regeneration, 686 demonstrating promotion of human mesenchymal stem cells differentiation into osteoblasts. In vivo studies were also carried out to evaluate the influence of the electroactive features of β-PVDF films on bone defect recovery, verifying that poled β-PVDF films leads to more defect closure and bone remodeling than nonpoled PVDF films and randomly oriented electrospun fiber mats.…”

Section: Biomedical Applications: Tissue Engineering and Antimicrobia...mentioning

confidence: 99%

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Smart and Multifunctional Materials Based on Electroactive Poly(vinylidene fluoride): Recent Advances and Opportunities in Sensors, Actuators, Energy, Environmental, and Biomedical Applications

Costa,

Cardoso,

Martins

et al. 2023

Chem. Rev.

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From scientific and technological points of view, poly(vinylidene fluoride), PVDF, is one of the most exciting polymers due to its overall physicochemical characteristics. This polymer can crystalize into five crystalline phases and can be processed in the form of films, fibers, membranes, and specific microstructures, being the physical properties controllable over a wide range through appropriate chemical modifications. Moreover, PVDF-based materials are characterized by excellent chemical, mechanical, thermal, and radiation resistance, and for their outstanding electroactive properties, including high dielectric, piezoelectric, pyroelectric, and ferroelectric response, being the best among polymer systems and thus noteworthy for an increasing number of technologies. This review summarizes and critically discusses the latest advances in PVDF and its copolymers, composites, and blends, including their main characteristics and processability, together with their tailorability and implementation in areas including sensors, actuators, energy harvesting and storage devices, environmental membranes, microfluidic, tissue engineering, and antimicrobial applications. The main conclusions, challenges and future trends concerning materials and application areas are also presented.

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Section: Applicationsmentioning

confidence: 99%

Section: Biomedical Applications: Tissue Engineering and Antimicrobia...mentioning

confidence: 99%

Smart and Multifunctional Materials Based on Electroactive Poly(vinylidene fluoride): Recent Advances and Opportunities in Sensors, Actuators, Energy, Environmental, and Biomedical Applications

Costa,

Cardoso,

Martins

et al. 2023

Chem. Rev.

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“…areas under the endothermic peaks of these PNCs which are listed in table 2) and taking the melting enthalpy ΔH mo of 100% crystalline PVDF materials (i.e. 104.8 J g −1 ) with the enthalpies ratio based relationship X c (%) = (ΔH m /ΔH mo ) × 100 [46,56]. These X c values of the PNC materials are reported in table 2 and also plotted against x (wt%) in figure 4(c).…”

Section: Pnc Films X (Wt%)mentioning

confidence: 99%

Broadband dielectric behaviour and structural characterization of PVDF/PMMA/OMMT polymer nanocomposites for promising performance nanodielectrics in flexible technology advances

Kumar

Sengwa

2023

Phys. Scr.

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Characterization of broadband dielectric behaviour of polymer nanocomposites (PNCs) is vital for the exploration of efficient nanodielectrics as energy storage, flexible dielectric substrates, and insulators in a wide range of advanced electronic device technologies. Accordingly, herein, PNC films based on poly(vinylidene fluoride) (PVDF) and poly(methyl methacrylate) (PMMA) blend matrix (80/20 wt/wt%) dispersed with 0, 2.5, 5, and 10 wt% organo-modified montmorillonite (OMMT) nanoclay are developed by state-of-the-art homogenized solution casting method. These PVDF/PMMA/OMMT compositions based flexible PNC films are characterized in detail by employing a scanning electron microscope (SEM) equipped with energy dispersive X-ray (EDX) device, X-ray diffractometer (XRD), Fourier transform infrared (FTIR) spectrometer, differential scanning calorimeter (DSC), inductance-capacitance-resistance (LCR) meter, and impedance/material analyzer (IMA). The SEM microimages, XRD traces, and FTIR spectra evidenced appreciable homogeneity and surface morphology, intercalated and exfoliated OMMT structures, and the α, β, and γ-phase crystallites of the PVDF in these complex semicrystalline PNCs. The DSC thermograms confirmed a significant alteration in the melting temperature and degree of crystallinity of the PVDF crystallites with the increased amount of OMMT in the 80PVDF/20PMMA blend host matrix. The broadband dielectric dispersion spectra over the frequency range of 20 Hz - 1 GHz explained the contribution of interfacial polarization in the complex dielectric permittivity at lower experimental frequencies, whereas at higher frequencies permittivity is ruled by dipolar polarization in these composites at 27 oC. The dielectric loss angle tangent and electric modulus spectra revealed an intense structural dynamics relaxation process in the radio frequency region. The influence of OMMT concentration on the dielectric permittivity and electrical conductivity is explored. The detailed dielectric and electrical characterization of these innovative semicrystalline composites with important structural and thermal properties revealed their immense potential as high-performance nanodielectrics for highlighting current applications of broadband frequency range electrical and electronic device technologies.

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“…In the preparation of these composites, mechanical drawing, solution casting, electrostatic spinning and other methods are usually used. Compared with other methods, the electrostatic spinning technique is simple to operate and can further increase the β-phase content under the polarization and stretching effect of high voltage electric field [22][23][24]. Pratihar et al [25] found that the addition of ZnO and MWCNT to PVDF can enhance the energy storage density and dielectric constant of the composite, etc.…”

Section: Introductionmentioning

confidence: 99%

Flexible piezoelectric sensor based on polyvinylidene fluoride/polyacrylonitrile/carboxy-terminated multi-walled carbon nanotube composite films for human motion monitoring

Huang,

Li,

Yang

et al. 2024

Nanotechnology

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Flexible piezoelectric devices have attracted much attention in the fields of intelligent devices and biomedicine because of their high sensitivity, stability, and flexibility. In this paper, a multifunctional flexible pressure sensor was prepared by adding polyacrylonitrile (PAN) and carboxylic-terminated multi-walled carbon nanotubes (c-MWCNTs) with polyvinylidene difluoride (PVDF) as the substrate. The β-phase content of PVDF/PAN blended fibers compounded with c-MWCNT was up to 95%. At the same time, when PAN was added, the mechanical properties of the composite fibers were constantly improved. The results show that the polymer blending method can improve the comprehensive properties of PVDF composite. The flexible sensor prepared from the PVDF/PAN/c-MWCNT composite film has an output voltage of 2.1 V and a current of 7 μA. The addition of c-MWCNT can largely improve the sensitivity of the sensor (4.19 V/N). The sensor is attached to the finger and shows good output performance under different degrees of bending of the finger. The maximum output voltage of the sensor is 0.4 V, 0.56 V and 1.15 V when the finger bending angle is 30°, 60°, and 90°, respectively. Moreover, the developed piezoelectric sensor can monitor large-scale movements of various parts of the human body. Therefore, this composite material shows potential in areas such as motion monitoring and energy storage devices.

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Stimuli-responsive piezoelectricity in electrospun polycaprolactone (PCL)/Polyvinylidene fluoride (PVDF) fibrous scaffolds for bone regeneration

Cited by 19 publications

References 51 publications

Smart and Multifunctional Materials Based on Electroactive Poly(vinylidene fluoride): Recent Advances and Opportunities in Sensors, Actuators, Energy, Environmental, and Biomedical Applications

Smart and Multifunctional Materials Based on Electroactive Poly(vinylidene fluoride): Recent Advances and Opportunities in Sensors, Actuators, Energy, Environmental, and Biomedical Applications

Broadband dielectric behaviour and structural characterization of PVDF/PMMA/OMMT polymer nanocomposites for promising performance nanodielectrics in flexible technology advances

Flexible piezoelectric sensor based on polyvinylidene fluoride/polyacrylonitrile/carboxy-terminated multi-walled carbon nanotube composite films for human motion monitoring

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