Stimuli-Responsive Nano-polymer Composite Materials Based on the Triazine Skeleton Structure Used in Drug Delivery

Peng, Xueying; Wei, Lulu; Jing, Xinbo; Cui, Lin; Wu, Jianning; Meng, Guihua; Liu, Zhiyong; Guo, Xuhong

doi:10.1007/s11837-018-3214-4

Cited by 6 publications

(2 citation statements)

References 39 publications

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“…Under the micro-acidic environment, the hydrophobic DOX was protonated after binding H + , resulting in the release of drugs. 38 The cumulative drug release rate of the Bio-RBCm@PDA@MSN-DOX + NIR group was 75.75%, which was notably higher than that of the non-irradiated NIR group. The Bio-RBCm@PDA@MSN-DOX could absorb NIR light and convert the absorbed energy into heat rapidly to cause cell membrane disintegration and accelerated molecular vibrations between drugs, which promoted drug release.…”

Section: Resultsmentioning

confidence: 85%

Long circulation and tumor-targeting biomimetic nanoparticles for efficient chemo/photothermal synergistic therapy

et al. 2022

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Section: Resultsmentioning

confidence: 85%

Long circulation and tumor-targeting biomimetic nanoparticles for efficient chemo/photothermal synergistic therapy

et al. 2022

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“…Conjugated triazine polymers (CTPs) are pH-responsive, highly biocompatible, and have a high loading capacity for DOX, possibly because of their π-π stacking interactions, high hydrophobicity, and high specific surface area. 65,146 Sharma et al 147 designed poly(allylamine hydrochloride) (PAH) and poly (methacrylic acid) (PMA) microcapsules using gold nanorod (NR)-modified calcium carbonate as a sacrificial template to encapsulate NR and two drugs for cancer treatment. Crucially, after laser irradiation, the capsule changed from a nonporous to a porous state.…”

Section: Reviewmentioning

confidence: 99%

Porous organic polymers for drug delivery: hierarchical pore structures, variable morphologies, and biological properties

et al. 2022

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Nano‐Micron Combined Hydrogel Microspheres: Novel Answer for Minimal Invasive Biomedical Applications

Liu,

Du,

Chen

et al. 2024

Macromol. Rapid Commun.

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Hydrogels, key in biomedical research for their hydrophilicity and versatility, have evolved with hydrogel microspheres (HMs) of micron‐scale dimensions, enhancing their role in minimally invasive therapeutic delivery, tissue repair, and regeneration. The recent emergence of nanomaterials has ushered in a revolutionary transformation in the biomedical field, which demonstrates tremendous potential in targeted therapies, biological imaging, and disease diagnostics. Consequently, the integration of advanced nanotechnology promises to trigger a new revolution in the realm of hydrogels. HMs loaded with nanomaterials combine the advantages of both hydrogels and nanomaterials, which enables multifaceted functionalities such as efficient drug delivery, sustained release, targeted therapy, biological lubrication, biochemical detection, medical imaging, biosensing monitoring, and micro‐robotics. Here, this review comprehensively expounds upon commonly used nanomaterials and their classifications. Then, it provides comprehensive insights into the raw materials and preparation methods of HMs. Besides, the common strategies employed to achieve nano‐micron combinations are summarized, and the latest applications of these advanced nano‐micron combined HMs in the biomedical field are elucidated. Finally, valuable insights into the future design and development of nano‐micron combined HMs are provided.

show abstract

Stimuli-Responsive Nano-polymer Composite Materials Based on the Triazine Skeleton Structure Used in Drug Delivery

Cited by 6 publications

References 39 publications

Long circulation and tumor-targeting biomimetic nanoparticles for efficient chemo/photothermal synergistic therapy

Long circulation and tumor-targeting biomimetic nanoparticles for efficient chemo/photothermal synergistic therapy

Porous organic polymers for drug delivery: hierarchical pore structures, variable morphologies, and biological properties

Nano‐Micron Combined Hydrogel Microspheres: Novel Answer for Minimal Invasive Biomedical Applications

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