Stimuli-responsive hybrid porous polymers based on acetals of polyvinyl alcohol and acrylic hydrogels

Samchenko, Yu. M.; Korotych, Olena; Kernosenko, L.; Kryklia, S.; Litsis, Olena O.; Skoryk, M. A.; Poltoratska, Tetiana; Пасмурцева, Н.

doi:10.1016/j.colsurfa.2018.02.015

Cited by 16 publications

(6 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…A visual examination of the residuals was conducted to check for obvious deviations from randomness or the possible presence of heteroscedasticity. The following were used in graphical residual analysis to assess the validity of linear and non-linear fits: (1) scatter plot of the response and predicted values versus the independent variable; (2) scatter plot of the residuals versus the independent variable; (3) scatter plot of the residuals versus the predicted values; (4) histogram of the residuals; and (5) normal probability plot of the residuals [54].…”

Section: Sar Measurements and Calculationmentioning

confidence: 99%

Evaluation of magnetic nanoparticles for magnetic fluid hyperthermia

Lanier

Korotych

Monsalve

et al. 2019

International Journal of Hyperthermia

116

View full text Add to dashboard Cite

Background: Magnetic nanoparticles (MNPs) generate heat when exposed to an alternating magnetic field. Consequently, MNPs are used for magnetic fluid hyperthermia (MFH) for cancer treatment, and have been shown to increase the efficacy of chemotherapy and/or radiation treatment in clinical trials. A downfall of current MFH treatment is the inability to deliver sufficient heat to the tumor due to: insufficient amounts of MNPs, unequal distribution of MNPs throughout the tumor, or heat loss to the surrounding environment. Objective: In this study, the objective was to identify MNPs with high heating efficiencies quantified by their specific absorption rate (SAR). Methods: A panel of 31 commercially available MNPs were evaluated for SAR in two different AMFs. Additionally, particle properties including iron content, hydrodynamic diameter, core diameter, magnetic diameter, magnetically dead layer thickness, and saturation mass magnetization were investigated. Results: High SAR MNPs were identified. For SAR calculations, the initial slope, corrected slope, and Box-Lucas methods were used and validated using a graphical residual analysis, and the Box-Lucas method was shown to be the most accurate. Other particle properties were identified and examined for correlations with SAR values. Positive correlations of particle properties with SAR were found, including a strong correlation for the magnetically dead layer thickness. Conclusions: This work identified high SAR MNPs for hyperthermia, and provides insight into properties which correlate with SAR which will be valuable for synthesis of next-generation MNPs. SAR calculation methods must be standardized, and this work provides an in-depth analysis of common calculation methods.

show abstract

Section: Sar Measurements and Calculationmentioning

confidence: 99%

Evaluation of magnetic nanoparticles for magnetic fluid hyperthermia

Lanier

Korotych

Monsalve

et al. 2019

International Journal of Hyperthermia

116

View full text Add to dashboard Cite

show abstract

“…Губчаті гідрогелі на основі ПВФ (рисунок 3б) відзначаються валентними та деформаційними коливаннями метильних груп, які мають піки з частотами 2770 cm -1 , 2940 cm -1 та 1365 cm -1 , 1431 cm -1 відповідно, інтенсивна полоса з хвильовим числом 1006 cm -1 відповідає валентним коливанням зв'язку -С-О-С-полівінілформальної групи. Широке поглинання з частотою близько 3470 cm -1 пояснюється валентними коливаннями О-Н групи непрореагованого залишку полівінілового спирту [16], також може бути зумовлено валентним і деформаційним вібраційним коливанням адсорбованої ПВФ губкою атмосферної води. Група смуг вібраційних коливань із піками поглинання 1006 cm -1 , 1066 cm -1 , 1130 cm -1 та 1172 cm -1 є відображенням ідентифікації циклічної послідовності зв'язків -С-О-С-О-С-у структурі полімеру [15].…”

Section: результатиunclassified

“…Група смуг вібраційних коливань із піками поглинання 1006 cm -1 , 1066 cm -1 , 1130 cm -1 та 1172 cm -1 є відображенням ідентифікації циклічної послідовності зв'язків -С-О-С-О-С-у структурі полімеру [15]. Свій внесок у пік, розташований близько 1006 cm -1 , можуть робити й деформаційні коливання непрореагованої С-О-Н групи [16].…”

Section: результатиunclassified

Antimicrobial effects of hydrogel implants incorporating gold nanoparticles and albucide and developed for reconstructive surgery in the orbit and periorbital area

Самченко,

Дибкова,

Малецький

et al. 2023

Oftalmol Zh

View full text Add to dashboard Cite

Background: It is important to develop orbital hydrogel implants capable of depositing drugs (particularly, antimicrobial and anticancer drugs). Purpose: To assess antimicrobial effects of hybrid hydrogel implants containing gold nanoparticles and albucide and developed for reconstructive surgery in the orbit and periorbital area. Material and Methods: A 30% aqueous solution of albucide was used in the study. Antimicrobial activity of synthesized hydrogels was determined using Escherichia coli ATCC 25922, Enterococcus faecalis ATCC 29213, Staphylococcus aureus ATCC 25923 and Pseudomonas aeruginosa ATCC 27853 strains. Results: All the synthesized samples of orbital hydrogel implants were sterile. The synthesized hydrogels and hydrogel nanocomposites with incorporated Au nanoparticles demonstrated bacteriostatic effects against E. Coli ATCC 25922, E. Faecalis ATCC 29213, and S. Aureus ATCC 25923 strains, and bactericidal effects against P. Aeruginosa ATCC 27853 strain. This study also demonstrated marked bactericidal effects of hybrid hydrogel implants incorporating both Au nanoparticles and albucide. Conclusion: Orbital hydrogel implants were found to be sterile after being sealed into polypropylene bags and steam sterilized at 121 °C for 20 minutes. Our findings of bacteriostatic and bactericidal effects of the synthesized hydrogels and hydrogel nanocomposites containing Au nanoparticles and albucide against bacterial strains of interest will allow for the absence of, or low probability of bacterial contamination in applications of these hydrogels in implants.

show abstract

“…Hydrogels are the hydrophilic three-dimensional polymeric networks that can absorb large amounts of water or other biological fluids, and they are excellent matrixes for drug delivery, growing and cultivating of cells, water purification, and creation of selective membranes . The pioneering studies of Haraguchi made it possible to achieve a significant improvement in the mechanical characteristics of polymer hydrogels by physical cross-linking using synthetic hectorite clay Laponite (Lap) nanoparticles (produced by BYK Additives Ltd.) instead of traditional chemical cross-linking agentsbifunctional monomers (e.g., N , N ′-methylene-bis-acrylamide).…”

Section: Introductionmentioning

confidence: 99%

Cross-Linked Hydrogels Based on PolyNIPAAm and Acid-Activated Laponite RD: Swelling and Tunable Thermosensitivity

et al. 2022

View full text Add to dashboard Cite

The effects of acid activation of Laponite RD (Lap) on the structure and properties of activated Lap nanoparticles (aLap) and the properties of polyNIPAA m hydrogels physically cross-linked by aLap have been studied. The acid activation of Lap by the sulfuric acid was done using the concentration of sulfuric acid within the interval C a = 0.525−14.58% for 10 h. For slightly activated samples (C a ≤ 1.25 wt %), the significant increase of the specific surface area (by ≈1.56 times) was accompanied with a significant decrease in both the values of the specific heat of immersion in water and n-decane. However, the hydrophilic properties of all samples S 0 −S 5 were still observed. Thermogravimetric analysis (TGA) and differential thermal analysis (DTA) data, Fourier transform infrared (FTIR) spectra, and X-ray diffraction (XRD) patterns demonstrated that the acid activation resulted in the destruction of the crystal lattice of Lap, leaching of magnesium and lithium, and formation of the amorphous phases. Moreover, the acid activation significantly affected aggregation and negative surface charges of the aLap faces in aqueous suspension. The effects of aLap on the swelling properties and cooperativity in the phase transitions of polyNIPAA m hydrogels cross-linked by aLap are also discussed. It was demonstrated that an increase in C a resulted in a significant increase in the equilibrium degree of swelling of the hydrogels and a decrease in the hydrogel phase-transition temperature from the swollen phase to the shrunken phase.

show abstract

Stimuli-responsive hybrid porous polymers based on acetals of polyvinyl alcohol and acrylic hydrogels

Cited by 16 publications

References 30 publications

Evaluation of magnetic nanoparticles for magnetic fluid hyperthermia

Evaluation of magnetic nanoparticles for magnetic fluid hyperthermia

Antimicrobial effects of hydrogel implants incorporating gold nanoparticles and albucide and developed for reconstructive surgery in the orbit and periorbital area

Cross-Linked Hydrogels Based on PolyNIPAAm and Acid-Activated Laponite RD: Swelling and Tunable Thermosensitivity

Contact Info

Product

Resources

About