Stimuli‐Responsive Delivery of Antimicrobial Peptides Using Polyelectrolyte Complexes
Alexander Antropenko,
Frank Caruso,
Paco Fernandez‐Trillo
Abstract:Antimicrobial peptides (AMPs) are antibiotics with the potential to address antimicrobial resistance. However, their translation to the clinic is hampered by issues such as off‐target toxicity and low stability in biological media. Stimuli‐responsive delivery from polyelectrolyte complexes offers a simple avenue to address these limitations, wherein delivery is triggered by changes occurring during microbial infection. The review first provides an overview of pH‐responsive delivery, which exploits the intrinsi… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.