Stimuli-responsive bio-based polymeric systems and their applications

Abstract

This article highlights the properties of stimuli-responsive bio-based polymeric systems and their main intelligent applications.

Predicting the Loading Capability of mPEG‐PDLLA to Hydrophobic Drugs Using Solubility Parameters†

“…In recent years, nanomedicine prepared by using polymers as a carrier has attracted widespread attention . Polymer nanomedicine can be used to improve the solubility of insoluble drugs, prepare sustained‐release preparations with long circulation time, prepare targeted drugs with high efficacy and load biological macromolecules . There are three main methods for preparing polymer nanomedicine: chemical bonding method, polyion complex method and physical encapsulation method.…”

Functionalized polyhedral oligosilsesquioxane (POSS) based composites for bone tissue engineering: synthesis, computational and biological studies

“…9,10 However, besides its outstanding chemical, physical and biological features, the applications of scaffolds based on this natural polysaccharide show some limitations mainly related to its low mechanical strength, quick hydrolysis and burst drug release which limit its use, as single component, in bone tissue engineering formulations. 11,12 In order to improve the mechanical behavior and biological stability of chitosan based scaffolds the 3D hydrogels have been reinforced with bioactive ceramic materials such as hydroxyapatite (HA), bioglass ceramic, silica nanoparticles, titanium dioxide and zirconium oxide. [13][14][15] Among the different inorganic compounds, silica nanoparticles have shown to improve mechanical properties of polymers by providing enhancement in their structure and increasing the bioactivity of the related composites.…”

Fabrication of open‐porous PCL/PLA tissue engineering scaffolds and the relationship of foaming process, morphology, and mechanical behavior

“…In the last decades, many methods and materials have been developed to fabricate tissue engineering scaffolds. Noting that different materials and processing parameters determined the microscopic morphology and mechanical properties . Therefore, it is necessary to optimize the processing parameters to obtain a scaffold with excellent properties as mentioned above …”