Stimulation of tumor necrosis factor-induced human myelogenous leukemic cell differentiation by high molecular weight PSK subfraction

Sakagami, Hiroshi; Ikeda, Mitsunori; Konno, Kunio

doi:10.1016/0006-291x(89)92352-8

Cited by 11 publications

(4 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The HTLV-1-producing cell line used in this experiment was c77 feline kidney cell line. 12) The mouse cell lines used as target cells were EL4 (CD4+ T-cell), 13) RLm1 (CD4+, CD8+ T-cell), 14) CTLL-2 (CD8+ T-cell), 15) J774.1 (macrophage), 16) Ba/F3 (Pro-B-cell), 17) DA-1 (myeloid cell), 18) WEHI-3 (myeloma cell), 19) NIH3T3 (fibroblast cell) 20) and B1(Leydig cell). 21) Human T-cell lines, Hut78 (CD4+, CD8−) 22) and Molt-4 (CD3+, CD4+), 23) were also used as target cells.…”

Section: Cells and Cell Culturementioning

confidence: 99%

Cell‐free Entry of Human T‐Cell Leukemia Virus Type 1 to Mouse Cells

Feng

Kabayama

Uchida

et al. 2001

Japanese Journal of Cancer Research

View full text Add to dashboard Cite

Human T-cell leukemia virus type 1 (HTLV-1) is the etiologic agent for adult T-cell leukemia and HTLV-1-associated myelopathy/tropical spastic paraparesis. Recently we infected newborn mice by inoculating HTLV-1-producing human cells, and found that T-cells, B-cells and granulocytes were infected in vivo. To understand the mechanism of viral-cell interaction and the pathogenesis of HTLV-1 using the mouse model, it is important to clarify the cellular tropism using a cell-free HTLV-1 transmission system. We employed a highly transmissible cell-free HTLV-1 produced by a feline kidney cell line, c77, and studied the susceptibility of 9 kinds of mouse cell lines, EL4, RLm1, CTLL-2, J774.1, DA-1, Ba/F3, WEHI-3, NIH3T3 and B1, and two kinds of human cell lines, Molt-4 and Hut78. HTLV-1 proviral sequence was found by PCR in all 9 mouse cell lines as well as in 2 human cell lines and viral entry was blocked with sera from an HTLV-1 carrier and an adult T-cell leukemia patient. Unexpectedly, mouse cell lines EL4 and RLm1 and human cell lines Molt-4 and Hut78 showed similar efficiency for viral entry. These results suggest a wide distribution of HTLV-1 receptor in mouse cells.

show abstract

Section: Cells and Cell Culturementioning

confidence: 99%

Cell‐free Entry of Human T‐Cell Leukemia Virus Type 1 to Mouse Cells

Feng

Kabayama

Uchida

et al. 2001

Japanese Journal of Cancer Research

View full text Add to dashboard Cite

show abstract

“…3) backbone and the b(1 ! 6) branch of polysaccharides are probably responsible for their anti-tumor activity [11][12][13].…”

Section: Introductionmentioning

confidence: 99%

Production, purification and partial characterization of a novel endo-β-1,3-glucanase from Agaricus brasiliensis

Shu

Lin

2006

Process Biochemistry

View full text Add to dashboard Cite

“…Recently, the biological properties of polysaccharides have been correlated with their release capability of TNF‐α of macrophage cell lines RAW 246.7 and J774 A.1 29. Furthermore, it seems that polysaccharides with high molecular weights have relatively high biological activities 30. We therefore adopted these approaches to evaluate the biological activity of exopolysaccharides produced by P. linteus .…”

Section: Introductionmentioning

confidence: 99%

Effects of sodium chloride on the production of bioactive exopolysaccharides in submerged cultures of Phellinus linteus

Shu

Hsu

2008

J of Chemical Tech & Biotech

View full text Add to dashboard Cite

BACKGROUND: Polysaccharides isolated from medicinal mushrooms have been shown to exhibit antitumour bioactivity, but the quality and quantity of these polysaccharides are affected by variations in medium composition and operational conditions in the submerged culture. This study was conducted to elucidate quantitatively the effects of sodium chloride (NaCl) supplementation on the production and quality of exopolysaccharides from the medicinal mushroom Phellinus linteus.

show abstract

Stimulation of tumor necrosis factor-induced human myelogenous leukemic cell differentiation by high molecular weight PSK subfraction

Cited by 11 publications

References 15 publications

Cell‐free Entry of Human T‐Cell Leukemia Virus Type 1 to Mouse Cells

Cell‐free Entry of Human T‐Cell Leukemia Virus Type 1 to Mouse Cells

Production, purification and partial characterization of a novel endo-β-1,3-glucanase from Agaricus brasiliensis

Effects of sodium chloride on the production of bioactive exopolysaccharides in submerged cultures of Phellinus linteus

Contact Info

Product

Resources

About