Stimulation of release of  -endorphin and oxytocin by prostaglandin F2  in cattle at parturition

Je, Aurich; Dobrinski, Ina; Ho, Hoppen; Grünert, E

doi:10.1530/jrf.0.0970161

Cited by 16 publications

(13 citation statements)

References 16 publications

(23 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Thus, no effect of exogenous PGF2-alpha on the secretion of ir-β-EP was observed in this study. These results are not consistent with a previous report by Aurich et al [22] in which cloprostenol stimulated a prompt increase in secretion of β-EP. They observed that the increase in β-EP release was transient and β-EP concentrations decreased by 20 min after PGF2-alpha administration.…”

Section: Discussioncontrasting

confidence: 99%

“…Lincoln, MRC Reproductive Biology Unit, Edinburgh, UK. Since the antiserum is crossreacted at 100% with human β-lipotropin, and about 30% of immunoreactivity extracted from bovine plasma eluted on HPLC at the position of β-lipotropin [22], the values were expressed as plasma immunoreactive β-EP (ir-β-EP) concentrations. All samples were measured in triplicate.…”

Section: Blood Samplingmentioning

confidence: 99%

See 1 more Smart Citation

Effects of Dystocia, Retained Placenta and Body Condition on Plasma .BETA.-Endorphin Profile in Periparturient Dairy Cows.

Osawa

Nakao

Moriyoshi

et al. 2000

Journal of Reproduction and Development

View full text Add to dashboard Cite

Abstract. The aims of this study were to determine profiles of plasma immunoreactive β-endorphin (ir-β-EP) during peripartum period in dairy cows, and to examine whether dystocia, retained placenta or body condition affects the plasma ir-β-EP level. Blood samples were collected from 21 Holstein-Friesian cows from day 180 of pregnancy until first ovulation. The cows were classified into two groups based on calving conditions and ir-β-EP patterns at parturition. Seven out of the 21 cows had normal parturition and 14 cows had abnormal parturition (dystocia and/or retained placenta). The proportion of cows which had ir-β-EP elevation at parturition tended to be higher in cows with abnormal parturition (11/14; 79%) than in those with normal parturition (3/7; 42%). Plasma cortisol level increased at parturition both in cows with ir-β-EP elevation and in cows without ir-β-EP elevation at parturition. Postpartum ir-β-EP concentrations in plasma were similar between cows with normal parturition and those with abnormal parturition, and between cows which had lost their body condition score (BCS) after calving and those which had maintained their BCS. In conclusion, abnormal parturition may affect plasma ir-β-EP level at parturition but not postpartum period.

show abstract

Section: Discussioncontrasting

confidence: 99%

Section: Blood Samplingmentioning

confidence: 99%

Effects of Dystocia, Retained Placenta and Body Condition on Plasma .BETA.-Endorphin Profile in Periparturient Dairy Cows.

Osawa

Nakao

Moriyoshi

et al. 2000

Journal of Reproduction and Development

View full text Add to dashboard Cite

show abstract

“…Increased -endorphin concentrations around parturition have been reported previously in cows (Aurich et al 1993), women (Chan et al 1993, Fajardo et al 1994, McLean et al 1994) and rats (Wardlaw & Frantz 1983). …”

Section: Figurementioning

confidence: 56%

“…Bacigalupo et al (1990) reported that pain intensity, scored by women during spontaneous labour, correlated positively with the concentration of plasma -endorphin and cortisol. Plasma levels of cortisol and -endorphin are elevated during labour in cattle (Hudson et al 1975, Aurich et al 1993) and goats (Hydbring & Olsson 1995), but there are no reports of any correlations between these hormones and the severity of labour in ruminants.…”

Section: Introductionmentioning

confidence: 99%

Hormonal changes during parturition in heifers and goats are related to the phases and severity of labour

Hydbring¹,

Madej²,

MacDonald³

et al. 1999

Journal of Endocrinology

View full text Add to dashboard Cite

Parturition is a natural event that involves stress and pain for the mother. We thus hypothesized that levels of stress hormones measured during parturition could reflect levels reached in response to severe discomfort and pain of other kinds as well. The aim of this study was therefore to determine whether plasma concentrations of cortisol, adrenaline, noradrenaline, -endorphin, met-enkephalin, vasopressin and oxytocin vary depending on the phase and severity of labour in dairy heifers (ten) and dairy goats (six), and how these hormones interact with each other. Blood samples were taken once a day for 3 days before labour and for 3 days afterwards and at predetermined phases during labour. All heifers delivered one calf and five of them needed obstetrical assistance. Two of the goats delivered one kid, and four had twins; all kidded without help. The cortisol concentration peaked when the calf and the first kid were born. In the heifers, plasma adrenaline increased after delivery, while the noradrenaline concentration did not change significantly in heifers that needed assistance, but increased during expulsion in heifers calving without help. In the goats, adrenaline and noradrenaline concentrations increased in association with expulsion of the first kid. The -endorphin concentration increased during labour in goats. In heifers that needed assistance, -endorphin concentration increased 1 h after labour but there was no change in heifers that did not need assistance. The met-enkephalin concentration was elevated during expulsion in heifers and fluctuated in the goats. Both oxytocin and vasopressin increased during expulsion in both groups of heifers, but vasopressin increased four times more in heifers needing assistance. In the goats, oxytocin reached its highest levels just as the feet of the first kid became visible, and vasopressin peaked as the head emerged. Parturition took longer in heifers that needed assistance than in those that did not. It is concluded that, even though the pattern of change differed between hormones during labour, the changes were related to the phases of labour. A longer labour therefore meant that the hormone concentrations stayed elevated for longer. Vasopressin reached high levels in goats and was the only hormone for which plasma concentrations were higher in heifers that needed assistance than in those that did not, indicating that this hormone is released in order to deal with the painrelated stress associated with labour.

show abstract

“…Maternal and fetal 3endorphin were correlated, as were its concentrations and fetal obstetric difficulty (81). During parturition in cows, there was a marked increase in 3-endorphin that paralleled the increase in oxytocin, even to the extent that it was released in an episodic manner in conjunction with uterine and abdominal contractions, suggesting that it interacted with oxytocin (26). In pigs, however, no change in 3-endorphin occurred with pregnancy (309).…”

Section: Developmentmentioning

confidence: 95%

Endogenous opiates: 1993

Olson

Kastin

1994

Peptides

View full text Add to dashboard Cite

This paper is the sixteenth installment of our annual review of research concerning the opiate system. It is restricted to papers published during 1993 that concern the behavioral effects of the endogenous opiate peptides, and does not include papers dealing only with their analgesic properties. The specific topics this year include stress; tolerance and dependence; eating; drinking; gastrointestinal, renal, and hepatic function; mental illness and mood; learning, memory, and reward; cardiovascular responses; respiration and thermoregulation; seizures and other neurological disorders; electrical-related activity; general activity and locomotion; development; immunological responses; and other behaviors.

show abstract

Stimulation of release of -endorphin and oxytocin by prostaglandin F2 in cattle at parturition

Abstract: Concentrations of \g=b\-endorphin and oxytocin were measured in plasma of cows before, during and after parturition.

Cited by 16 publications

References 16 publications

Effects of Dystocia, Retained Placenta and Body Condition on Plasma .BETA.-Endorphin Profile in Periparturient Dairy Cows.

Effects of Dystocia, Retained Placenta and Body Condition on Plasma .BETA.-Endorphin Profile in Periparturient Dairy Cows.

Hormonal changes during parturition in heifers and goats are related to the phases and severity of labour

Endogenous opiates: 1993

Contact Info

Product

Resources

About