Stimulation of rat liver growth by a 1,3-dithiole derivative, KZ-1026.

Abstract

Abstract-The oral administration of 2-(1,3-dithiol-2-ylidene)-1-phenyl-1,3 butanedione (KZ-1026) to normal rats at doses of 50, 100 and 200 mg/kg/day for 3 days accelerated liver enlargement in association with a dose-dependent increase