Stimulants associated with reduced risk of hospitalization for motor vehicle accident injury in patients with obstructive sleep apnea-a nationwide cohort study

Lin, Yi; Chen, Tien‐Yu; Chien, Wu Chien; Chung, Chi Hsiang; Chang, Hsin‐An; Kao, Yu Chen; Tsai, Chien‐Sung; Lin, Chih Sheng; Tzeng, Nian Shen

doi:10.1186/s12890-019-1041-1

Cited by 20 publications

(17 citation statements)

References 46 publications

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“…The National health insurance (NHI) Program is a mandatory and universal health insurance program in Taiwan, which has been has been operative since 1995, that covered contracts with 97% of the medical providers with approximately 23 million beneficiaries, or more than 99% of the population 26 . The details of this program were documented in several previous studies [27][28][29][30][31][32][33][34][35][36][37] . The NHIRD contains comprehensive and detailed data regarding the total outpatients and inpatients.…”

Section: Data Sourcesmentioning

confidence: 99%

What could we learn from SARS when facing the mental health issues related to the COVID-19 outbreak? A nationwide cohort study in Taiwan

et al. 2020

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There were several studies about the psychiatric and mental health issues related to the severe adult respiratory syndrome (SARS) outbreak in 2003, however, the association between SARS and the overall risk of psychiatric disorders and suicides has, as yet, to be studied in Taiwan. The aim of this study is to examine as to whether SARS is associated with the risk of psychiatric disorders and suicide. A total of 285 patients with SARS and 2850 controls without SARS (1:10) matched for sex, age, insurance premium, comorbidities, residential regions, level of medical care, and index date were selected between February 25 and June 15, 2003 from the Inpatient Database Taiwan’s National Health Insurance Research Database. During the 12-year follow-up, in which 79 in the SARS cohort and 340 in the control group developed psychiatric disorders or suicide (4047.41 vs. 1535.32 per 100,000 person-years). Fine and Gray’s survival analysis revealed that the SARS cohort was associated with an increased risk of psychiatric disorders and suicide, and the adjusted subdistribution HR (sHR) was 2.805 (95% CI: 2.182–3.605, p < 0.001) for psychiatric disorders and suicide. The SARS cohort was associated with anxiety, depression, sleep disorders, posttraumatic stress disorder/acute stress disorder (PTSD/ASD), and suicide. The sensitivity analysis revealed that the SARS group was associated with anxiety, depression, sleep disorders, PTSD/ASD, and suicide after the individuals with a diagnosis of psychiatric disorders and suicide were excluded within the first year, and with anxiety, depression, and sleep disorders, while those in the first five years were excluded. In conclusion, SARS was associated with the increased risk of psychiatric disorders and suicide.

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Section: Data Sourcesmentioning

confidence: 99%

What could we learn from SARS when facing the mental health issues related to the COVID-19 outbreak? A nationwide cohort study in Taiwan

et al. 2020

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“…The NHIRD, which contains all the claims data of the beneficiaries, uses the International Classification of Diseases, ninth Revision, Clinical Modification (ICD-9-CM) codes to record the diagnoses (Chinese Hospital Association, 2000). The details of the program have been documented in previous studies (Chen et al, 2020;Chien et al, 2017;Kao et al, 2018;Y. C. Lin et al, 2020;Wan, Chien, Chung, Yang, & Tzeng, 2020;Wang et al, 2020;Yang et al, 2019;Yeh et al, 2020).…”

Section: Data Sourcesmentioning

confidence: 99%

Eating disorders and the risk of esophageal and stomach cancers‐A nationwide, population‐based cohort study in Taiwan

Yeh

Chien

Chung

et al. 2020

Intl J Eating Disorders

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Background: Previous studies have shown elevated cancer risk in anorexia nervosa but the literature on other eating disorders (EDs) is scarce. This study aimed to investigate the association between all EDs and esophageal, stomach, and other cancers.Methods: We used a retrospective cohort design, based on a two-million randomized longitudinal health insurance dataset, a sub-dataset of Taiwan's National Health Insurance Research Database. From all the potential participants aged 20 years or more, a total of 6,628 participants were enrolled, including 1,657 patients with EDs, with sex-, age-, and indexed date-matched (1:3) 4,971 controls. Each participant was individually tracked from 2000 to 2015 to identify incident cases of cancers, including esophageal cancer (EC), stomach cancer (SC), and all other cancers (AOC). The multivariate Cox proportional hazards model was employed to estimate the hazard ratios (HRs) and 95% confidence intervals (CIs) for the association between EDs and cancer.Results: Of the total 6,628 enrollees, 222 in 1,657 individuals with EDs and 810 in the 4,971 non-ED control individuals developed cancer (1,262.40 vs. 1,472.15 per 100,000 person-years), and the Kaplan-Meier survival analysis was not statistically significant (log-rank, p = .324). However, after adjusting for covariates, the risk of EC and SC among the individuals with an ED was significantly higher, with adjusted HRs of 5.32 (95% CI: 1.07-26.49, p < .001) and 4.61 (95% CI: 1.91-11.14, p < .001), respectively. EDs were not associated with other cancers. Conclusions:This study provides evidence for the association between EDs and the risk for EC and SC. Further research on mechanisms and prevention is therefore needed.

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“…The details of the program have been documented in previous studies. [24][25][26][27][28][29][30][31][32][33] This study was a retrospective matched-cohort design. Patients with ARD were selected from January 1 to December 31, 2000, according to the ICD-9-CM codes (Table S1) as: amphetamine dependence, amphetamine abuse, and drug psychosis between January 1, 2000 and December 31, 2000, without other substance use disorders within one year before or after the diagnosis of drug psychosis, with reference from one previous study.…”

Section: Study Design and Sampled Participantsmentioning

confidence: 99%

Association between amphetamine‐related disorders and dementia‐a nationwide cohort study in Taiwan

Tzeng

Chien

Chung

et al. 2020

Ann Clin Transl Neurol

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Objective We have conducted a study to clarify the association between amphetamine‐related disorders (ARD) and the risk of developing dementia. Methods This study used a retrospective cohort design by using Taiwan’s National Health Research Institute Database. A random sample of 68,300 subjects between January 1, 2000, and December 31, 2015, was obtained, comprising of 17,075 patients with ARD, and 51,225 controls without ARD (1:3), matched for gender and age group. After adjusting for covariates, a Fine and Gray’s survival analysis (competing with mortality) was used to compare the risk of dementia during a 15‐year follow‐up period. Results In the present study, 1,751 of 17,075 patients with ARD and 2,147 of 51,225 in the control group without ARD (883.10 vs 342.83 per 100,000 person‐years) developed dementia. ARD cohort was more likely to develop dementia (hazard ratio = 4.936 [95% CI: 4.609–5.285, P < 0.001). After adjusting for gender, age groups, education, monthly insured premiums, urbanization level, geographic region, comorbidities, the hazard ratio for ARD patients was 5.034 (95% CI: 4.701–5.391, P < 0.001). ARD has been associated with overall dementia, Alzheimer dementia, vascular dementia, and other dementia. Both the amphetamine use disorder and amphetamine‐induced psychotic disorders were associated with the risk of overall dementia, Alzheimer dementia, vascular dementia, and other dementia. Interpretation This study shows that patients with ARD, both the amphetamine use disorder and the amphetamine‐induced psychotic disorder, may have a nearly fivefold risk of developing dementia, including Alzheimer dementia and other types of dementia.

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Stimulants associated with reduced risk of hospitalization for motor vehicle accident injury in patients with obstructive sleep apnea-a nationwide cohort study

Cited by 20 publications

References 46 publications

What could we learn from SARS when facing the mental health issues related to the COVID-19 outbreak? A nationwide cohort study in Taiwan

What could we learn from SARS when facing the mental health issues related to the COVID-19 outbreak? A nationwide cohort study in Taiwan

Eating disorders and the risk of esophageal and stomach cancers‐A nationwide, population‐based cohort study in Taiwan

Association between amphetamine‐related disorders and dementia‐a nationwide cohort study in Taiwan

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