Still a threatening opioid wave: it is time for the protagonist to step up!

Lee, Joon-Ho

doi:10.3344/kjp.22403

Cited by 3 publications

(3 citation statements)

References 6 publications

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“…Fentanyl, known for its high risk of abuse [ 22 ], was the second most commonly prescribed opioid when categorized by ingredient (combining all formulations). The abuse of fentanyl has become a significant global issue [ 22 ], and has recently emerged as a societal issue in South Korea as well [ 23 ]. Not only oral and intravenous formulations of fentanyl but also transdermal fentanyl patches have been identified as significant sources of abuse [ 22 ].…”

Section: Discussionmentioning

confidence: 99%

Current status of opioid prescription in South Korea using narcotics information management system

Yoon,

Kim,

Yoon

et al. 2023

Korean J Pain

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Background Recognizing the seriousness of the misuse and abuse of medical narcotics, the South Korean government introduced the world's first narcotic management system, the Narcotics Information Management System (NIMS). This study aimed to explore the recent one-year opioid prescribing patterns in South Korea using the NIMS database. Methods This study analyzed opioid prescription records in South Korea for the year 2022, utilizing the dispensing/administration dataset provided by NIMS. Public data from the Korean Statistical Information Service were also utilized to explore prescription trends over the past four years. The examination covered 16 different opioid analgesics, assessed by the total number of units prescribed based on routes of administration, type of institutions, and patients’ sex and age group. Additionally, the disposal rate for each ingredient was computed. Results In total, 206,941 records of 87,792,968 opioid analgesic units were analyzed. Recently, the overall quantity of prescribed opioid analgesic units has remained relatively stable. The most prescribed ingredient was oral oxycodone, followed by tapentadol and sublingual fentanyl. Tertiary hospitals had the highest number of dispensed units (49.4%), followed by community pharmacies (40.2%). The highest number of prescribed units was attributed to male patients in their 60s. The disposal rates of the oral and transdermal formulations were less than 0.1%. Conclusions Opioid prescription in South Korea features a high proportion of oral formulations, tertiary hospital administration, pharmacy dispensing, and elderly patients. Sustained education and surveillance of patients and healthcare providers is required.

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Section: Discussionmentioning

confidence: 99%

Current status of opioid prescription in South Korea using narcotics information management system

Yoon,

Kim,

Yoon

et al. 2023

Korean J Pain

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“…Compelling evidence suggests that opioids may even worsen hyperalgesia and other centralized pain conditions commonly associated with FM, leading to a phenomenon known as opioid-induced hyperalgesia [ 21 ]. There is a growing societal concern about the misuse of opioids [ 22 ]. Regarding the high frequency of opioid usage observed in our study, it is inferred that many patients who do not respond to treatment via various departments seek finally the department of anesthesiology and pain medicine, particularly for refractory cases due to the clinical practice characteristics in Korea.…”

Section: Discussionmentioning

confidence: 99%

The current status of fibromyalgia in Korea: an electronic population health data study in Korea

Lee,

Yang

et al. 2023

Korean J Pain

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Background Fibromyalgia (FM) is a complex disorder characterized by widespread chronic pain and tenderness in the muscles, ligaments, and soft tissues. It is a chronic pain condition often accompanied by other symptoms and comorbidities. To effectively manage FM, it is crucial to obtain fundamental epidemiological data pertaining to the target population. Therefore, this study was conducted to elucidate the epidemiological characteristics of FM in the Korean population. Methods Population-based medical data of 51,276,314 subscribers to the National Health Insurance Service of Korea from 2014 to 2018 were used in this study. Results The overall incidence of FM ranged from 441 (2014) to 541 (2018) cases per 100,000 person-years, with a higher prevalence observed among female patients compared to male patients. The incidence gradually increased until middle age, followed by a decrease. The highest incidence rates were observed in the fifth decade of life for females and the sixth decade of life for males. When categorizing the affected parts of the body, the shoulder region was observed to be the most frequently affected. A comparison of the drug prescriptions based on medical specialty showed that antidepressants were the most commonly prescribed medications. The management of FM leads to consistent increases in medical expenses, regional disparities, and variations in prescription patterns across different medical specialties. Conclusions The findings of this study will not only contribute to the understanding of FM characteristics but also provide a vital foundation for efficient management of FM in Korea.

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“…What was the rationale for using a primarily opioid-based analgesic regimen without the automatic inclusion of regular non-opioid adjuncts? Can it be recommended in a climate where opioid misuse has, for example, contributed to a reversal in the yearon-year reduction in general mortality in the USA and appears to be a growing problem in South Korea [4,5]? We do, however, acknowledge the addition of non-opioid-based analgesic drugs in response to pain scores ≥ 4 on the postoperative ward.…”

mentioning

confidence: 99%

Analgesia nociception index for intra‐operative remifentanil dose and pain after gynaecological laparotomy

2023

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Still a threatening opioid wave: it is time for the protagonist to step up!

Cited by 3 publications

References 6 publications

Current status of opioid prescription in South Korea using narcotics information management system

Current status of opioid prescription in South Korea using narcotics information management system

The current status of fibromyalgia in Korea: an electronic population health data study in Korea

Analgesia nociception index for intra‐operative remifentanil dose and pain after gynaecological laparotomy

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