Stilbenoids in the stem bark of Hopea parviflora

Occurrence of C-Glucoside of Resveratrol Oligomers in Hopea parviflora

“…The lower reactivities of G and H can be explained by radical instability and neighboring bulky substituents (O-glucopyranosyloxy group), respectively (Chart 1, (d)). In addition to 1-4, nine known compounds were isolated and their structures identified as malibatol (5), 16) ampelopsin A (6), 10,20,21) balanocarpol (7), 21) piceid (8), vateriaphenol B (9), 6) (Ϫ)-hopeaphenol (10), 22) pauciflorol C (11), 5,14) grandiphenol A (12), 14) and vatalbinoside A (13) 12) by spectral analysis and comparison with authentic samples.…”

“…Our previous phytochemical study demonstrated that the structural diversity is due to the oligomerization degree of the blocking unit of resveratrol, which generates a skeletal variation and complicated stereostructures, and the production of O-and C-glucosides. [1][2][3][4][5][6][7][8][9][10][11][12][13][14] The genus Hopea belongs to Shoreae, one of the two major tribes of the subfamily Dipterocarpoideae, with about 102 species distributed throughout southeast Asia, especially in Indonesia and Malaysia, southern China, southern and eastern India, and Sri Lanka. 15) During this decade, this genus has been well documented to be a good source of biologically active stilbenoids.…”

“…18) Although accumulation of our chemical library originated from the other tribe of Dipterocarpoideae, phytochemical aspects of Shoreae, including the genus Hopea, have not been comprehensively expanded. Furthermore, our limited studies on Hopea (H. parviflora in 2000 10) and H. utilis in 2001 9) ) that deal with a narrow sphere of polarity describing the structure of resveratrol oligomers. In the current study, we focused on the highly polar components present in this tribe and reinvestigated the methanol extract of the stem of H. parviflora.…”

“…In the current study, we focused on the highly polar components present in this tribe and reinvestigated the methanol extract of the stem of H. parviflora. This study reports the isolation of four new stilbene glucosides [hopeasides A (1)-D (4)] along with nine known compounds (5)(6)(7)(8)(9)(10)(11)(12)(13). Their structures were elucidated by extensive spectroscopic methods, including 1D-and 2D-NMR experiments and high-resolution electron spray ionization mass spectra (HR-ESI-MS) analysis, and clarified by computer-aided molecular modeling.…”

Antibacterial and Cytotoxic Potencies of Stilbene Oligomers From Stem Barks of Baoti (Dryobalanops Lanceolata) Growing in Kendari, Indonesia

“…In the same way as structure determination of balanocarpol, the compounds 2, 3, 4, and 5 are e-viniferin [24], a-viniferin [25], vaticanol B [26], and hopeaphenol [27], respectively. Refers to a previous study [20], three compounds were isolated from D. lanceolata from Kendari, namely, balanocarpol, e-viniferin, and a-viniferin, not reported from Malaysia's D. lanceolata.…”