Stiff left atrial syndrome after catheter ablation for atrial fibrillation: Clinical characterization, prevalence, and predictors

Gibson, Douglas; Biase, Luigi Di; Mohanty, Prasant; Patel, J.; Bai, Rong; Sánchez, Javier; Burkhardt, J. David; Heywood, J. Thomas; Johnson, Allen D.; Rubenson, David; Horton, Rodney; Gallinghouse, G. Joseph; Beheiry, Salwa; Curtis, Guy P.; Cohen, David; Lee, Mark Y.; Smith, Michael; Gopinath, Devi; Lewis, William R.; Natale, Andrea

doi:10.1016/j.hrthm.2011.02.026

Cited by 186 publications

(176 citation statements)

References 13 publications

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“…1110 Moreover, a recent study has reported a series of patients who developed LA diastolic dysfunction and pulmonary hypertension following AF ablation. 1111 The precise cause of “stiff LA syndrome” or a “noncompliant LA” and methods to prevent it will clearly be an area for further study going forward.…”

Section: Outcomes Of Af Ablation In Populations Not Well Represented mentioning

confidence: 99%

“…1110,1111,1270,1271,1272,1273 One early report described a series of three patients with unexplained exertional dyspnea, LA hypertension, and large V waves on LA pressure or pulmonary capillary wedge pressure (PCWP) tracings after multiple surgical LA ablation procedures. 1271 A subsequent study prospectively collected 1380 consecutive patients undergoing ablation, obtaining echocardiograms before and after ablation to assess for pulmonary hypertension.…”

Section: Section 10: Complicationsmentioning

confidence: 99%

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2012 HRS/EHRA/ECAS Expert Consensus Statement on Catheter and Surgical Ablation of Atrial Fibrillation: Recommendations for Patient Selection, Procedural Techniques, Patient Management and Follow-up, Definitions, Endpoints, and Research Trial Design

Calkins,

Kuck,

Cappato

et al. 2012

Heart Rhythm

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Section: Outcomes Of Af Ablation In Populations Not Well Represented mentioning

confidence: 99%

Section: Section 10: Complicationsmentioning

confidence: 99%

2012 HRS/EHRA/ECAS Expert Consensus Statement on Catheter and Surgical Ablation of Atrial Fibrillation: Recommendations for Patient Selection, Procedural Techniques, Patient Management and Follow-up, Definitions, Endpoints, and Research Trial Design

Calkins,

Kuck,

Cappato

et al. 2012

Heart Rhythm

Self Cite

1,754

1,468

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“…Treatment of patients with the stiff left atrial syndrome is very challenging and essentially consists of diuretics 3, 4, 5. Interestingly, this patient was oligosymptomatic despite impressive haemodynamics.…”

Section: Discussionmentioning

confidence: 96%

“…typically occurring several years after catheter ablation due to scarring with reduction or loss of left atrial compliance and contractility 3, 4, 5. This complication occurs after extensive ablation also within the left atrium3 and surgical maze procedures 4.…”

Section: Discussionmentioning

confidence: 99%

“…Importantly, administration of specific PAH therapies in patients with PH due to left heart diseases even can cause harm 2. Herein, we present the case of a patient with PH in the context of the stiff left atrial syndrome 3, 4, 5. The aim of this case presentation is, on the one hand, to describe this rare disease and, on the other hand, to highlight the importance of a systemic diagnostic approach to the patient with suspected PH using a combination of invasive haemodynamics and non‐invasive imaging.…”

Section: Introductionmentioning

confidence: 99%

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Pulmonary hypertension in stiff left atrial syndrome: pathogenesis and treatment in one

Maeder

Nägele

Rohner³

et al. 2017

ESC Heart Failure

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We present the rare case of a patient with pulmonary hypertension in the context of the stiff left atrial syndrome after extensive catheter ablation, a unique constellation characterized by high pulmonary artery and pulmonary artery wedge pressures due to left atrial dysfunction but normal left ventricular end‐diastolic pressure, normal mitral valve, and absence pulmonary vein stenosis. This patient was surprisingly oligosymptomatic, however, which may have been due to a persistent post‐puncture atrial septal defect, which may have allowed for controlled left atrial decompression, which is in line with the novel concept of the catheter‐based creation of an intracardiac shunt as a treatment for heart failure.

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Charting long‐term success and the challenge of monitoring outcomes

Deisenhofer

2015

Practical Guide to Catheter Ablation of Atrial Fibrillation

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Stiff left atrial syndrome after catheter ablation for atrial fibrillation: Clinical characterization, prevalence, and predictors

Cited by 186 publications

References 13 publications

2012 HRS/EHRA/ECAS Expert Consensus Statement on Catheter and Surgical Ablation of Atrial Fibrillation: Recommendations for Patient Selection, Procedural Techniques, Patient Management and Follow-up, Definitions, Endpoints, and Research Trial Design

2012 HRS/EHRA/ECAS Expert Consensus Statement on Catheter and Surgical Ablation of Atrial Fibrillation: Recommendations for Patient Selection, Procedural Techniques, Patient Management and Follow-up, Definitions, Endpoints, and Research Trial Design

Pulmonary hypertension in stiff left atrial syndrome: pathogenesis and treatment in one

Charting long‐term success and the challenge of monitoring outcomes

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