Sticking - pulling strategy for assessment of combined medicine for management of tough symptoms in COVID-19 Pandemic using different windows of spectrophotometric Platform-Counterfeit products' detection

Spider diagram and sustainability evaluation of UV-methods strategy for quantification of aspirin and sildenafil citrate in the presence of salicylic acid in their bulk and formulation

“…In the light of green analytical chemistry (GAC) [ 25 ], UV-methods provide economic green analytical methods instead of chromatographic ones, because they do not use more solvents, do not generate a lot of waste, and do not need additional equipment. So they are considered as cost-saving methods [ [26] , [27] , [28] , [29] , [30] , [31] ].…”

Greenness-sustainability metrics for assessment smart-chemometric spectrophotometric strategy for evaluation of the combination of six gastric proton-pump inhibitors with two selected impurities

“…Additionally, UPLC, UPLC–MS/MS [25] , [26] , [27] , LC-MS/MS, and LC-DAD techniques were applied [28] , [29] , [30] . Several reports also highlight eco-friendly approaches such as derivative analysis, ratio spectra, and mathematical modeling in both binary and ternary mixtures with other drugs [31] , [32] , [33] . On the other hand, none of these methods possesses the capability to determine OME, ESO, LAN, PAN, RAB, and DEX along with two selected official impurities,4-DES-Imp., and RAB-Imp.…”

Coupling of physical extraction and mathematical filtration in spectrophotometric analysis of natural therapy essential for prophylaxis and treatment of COVID-19 infection - Comparative study along with greenness evaluation

“…This technique is based on regaining the parent spectrum (PS) of severely overlapped spectra of analytes in the mixtures followed by concentration detection at their absorbance maxima with satisfactory accuracy and precision via recently introduced resolution tool called factorized spectrum (FS) used in quality control laboratories. Spectrophotometric analysis is widely used in determination of various pharmaceutical preparation owing to their well-known benefits such as user friendly, simplicity, cost effective, abatement of expensive reagents or complicated software [ [41] , [42] , [43] , [44] , [45] ]. The obtained results of the proposed methods using different extraction scheme along with those attained by the reported method were set side by side through a well-designed comparative study to assure the applicability and efficacy of the proposed methods.…”