Stevens-Johnson syndrome: A review of 14 adult cases with one fatal outcome

Sawicki, Jakub; Ellis, Anne K.

doi:10.1016/j.anai.2012.12.017

Cited by 3 publications

(4 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Twenty-five publications describing a total of 27 patients were included in the review: 23 case reports having one patient in each and two case series 6,37 (details of two patients from each case series were relevant for this review). An overview of the cases is provided in Table 2.…”

Section: Resultsmentioning

confidence: 99%

“…The results of the literature search are shown in Figure 1. Twenty‐five publications describing a total of 27 patients were included in the review: 23 case reports 14–36 having one patient in each and two case series 6,37 (details of two patients from each case series were relevant for this review). Figure 2 shows the quality assessment of the identified cases.…”

Section: Resultsmentioning

confidence: 99%

“…18 The diagnosis of different degrees of epidermal necrolysis relies on the clinical assessment in combination with skin biopsy. 7,37 The distinction among SJS, SJS/TEN overlap, and TEN based on histopathological findings is not possible. 7 Identification of the culprit drug may be straightforward in cases where a single drug is implicated, but difficulties are posed by a patient who has been exposed to multiple drugs.…”

Section: Discussionmentioning

confidence: 99%

“…The diagnosis of different degrees of epidermal necrolysis relies on the clinical assessment in combination with skin biopsy 7,37 . The distinction among SJS, SJS/TEN overlap, and TEN based on histopathological findings is not possible 7 .…”

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

Stevens‐Johnson syndrome and toxic epidermal necrolysis associated with the use of macrolide antibiotics: a review of published cases

Pejčić

2020

Int J Dermatology

View full text Add to dashboard Cite

Macrolides are one of the most commonly prescribed antibiotics. In several studies, their use was associated with the occurrence of Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). This review aimed to explore and summarize available cases of SJS/TEN suspected to be associated with the use of macrolide antibiotics reported in the literature. Electronic searches were conducted in PubMed/MEDLINE, Web of Science, Scopus, and Serbian Citation Index (SCIndeks). Twenty-five publications describing a total of 27 patients were included. Cases of SJS/TEN which satisfied inclusion criteria were found for azithromycin (n = 11), clarithromycin (n = 7), erythromycin (n = 5), roxithromycin (n = 2), and telithromycin (n = 2). The age of the patients ranged from 2 to 77 years (median: 29 years). There were 14 female (51.9%) and 13 male (48.1%) patients. SJS was diagnosed in 16 patients (59.3%), TEN in 10 patients (37.0%), and SJS/TEN overlap in one patient (3.7%). Time to onset of the first symptoms ranged from 1 to 14 days (median: 3 days). All patients received some form of supportive and symptomatic care. Systemic corticosteroids were reported to be administered in 12 patients (44.4%) and intravenous immunoglobulin in five patients (18.5%). Three patients (11.1%) died. Considering that SJS/TEN is a severe and potentially life-threatening reaction, physicians should be aware that they could be adverse effects of macrolide antibiotics and keep in mind that prompt recognition of SJS/TEN and discontinuation of the culprit drug in combination with supportive care is essential.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%