Steroids from the stem of Nymphaea stellata

Chowdhury, Badrun Naher; Haque, Mozammel; Sohrab, Hossain; Afroz, Farhana; Al-Mansur, Muhammad Abdullah; Sultana, Tamanna; Hasan, Choudhury Mahmood

doi:10.3329/jbas.v37i1.15687

Cited by 6 publications

(3 citation statements)

References 12 publications

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“…Flowers were reported for antidiabetic, antihepatotoxicity and anti-inflammatory activities [7][8][9][10][11][12] and leaves were reported for antimicrobial activity 13 . Three steroids, namely 24-ethyl-5α-cholestan-3one, 5α-stigmast-22-en-3-one, stigmast-5,22-dien-3-one have been isolated from N. nouchali stem bark showing antimicrobial and cytotoxic activities 14 . The seeds, however, are said to be stomachic and restorative, and they are prescribed as a diet for diabetes mellitus in the Ayurvedic system of medicine 15 .…”

Section: Introductionmentioning

confidence: 99%

Qualitative and quantitative determination of secondary metabolites and antioxidant potential of Nymphaea nouchali flowers

Singh

Jain

2018

J. Drug Delivery Ther.

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In the Indian ayurvedic system of medicine, Nymphaea nouchali is used for the treatment of diabetes, inflammation, liver disorders, cutaneous diseases, blenorrhagia, urinary disorders, menorrhagia, menstruation problem, as an aphrodisiac, bitter tonic, antimicrobial agent and anti antihepatotoxic effect. The aim of the present study is to examine Nymphaea nouchali flowers for phytochemical profile, in vitro antioxidant activities. Qualitative analysis of various phytochemical constituents and quantitative analysis of total phenolics and flavonoids were determined by the well-known test protocol available in the literature. Quantitative analysis of phenolic and flavonoids was carried out by Folins Ciocalteau reagent method and aluminium chloride method respectively. The In vitro antioxidant activity of ethanolic extract of the flowers was assessed against nitric oxide, hydrogen peroxide assay using standard protocols. Phytochemical analysis revealed the presence of phenols, flavonoids, tannins, saponins, alkaloids, fixed oil and fats. The total phenolics content of flowers ethanolic extract was (18.4 mg/100mg), followed by flavonoids (12.4mg/100mg). The activities of ethanolic flowers extract against nitric oxide and hydrogen peroxide were concentration dependent with IC50 values of 68.39 and 64.54 μg/ml respectively. The present study concluded that the crude extract of Nymphaea nouchali is a potential source of natural antioxidants and this justifies its use in folkloric medicine. Keywords: Nymphaea nouchali, Phytochemical, Antioxidant, Nitric oxide, Hydrogen peroxide, Phenols, Flavonoids

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Section: Introductionmentioning

confidence: 99%

Qualitative and quantitative determination of secondary metabolites and antioxidant potential of Nymphaea nouchali flowers

Singh

Jain

2018

J. Drug Delivery Ther.

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“…Flowers of this plant has been extensively investigated and found to possess antioxidant [8] , antidiabetic [9] , anti-inflammatory [10] and antihepatotoxic activities [11] . Three steroids, namely 24-ethyl-5α-cholestan-3-one, 5α-stigmast-22-en-3-one, stigmast-5,22-dien-3-one have been isolated from N. stellata stem bark showing antimicrobial and cytotoxic activities [12] . The seeds, however, are said to be stomachic and restorative, and they are prescribed as a diet for diabetes mellitus in the Ayurvedic system of medicine [13] .…”

Section: Introductionmentioning

confidence: 99%

Phytochemical analysis and In vitro antioxidant acitivity of hydroalcoholic seed extract of Nymphaea nouchali Burm. f.

Parimala

Shoba

2013

Asian Pacific Journal of Tropical Biomedicine

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“…[76] Gallic acid contains several health promoting properties like anticancer, [77] antioxidant and antimelanogenic [78] , reduce inflammation [79] and protection from microbes. [80] Quercitrin is reported to exhibit antiinflammatory, immunomodulatory activities along with analgesic, [81] and antioxidant effects. [82] Steroids have been found in the stem of N. stellata, including stigmastenone, stigmastanol, stigmast-5,22-dien-3-one.…”

Section: Phytochemistrymentioning

confidence: 99%

Water Lily (Nymphaea nouchali Burm. f): An Ancient Treasure of Food and Medicine

Kiranmai¹,

Sandhyarani²,

Tiwari³

2023

Pharmacogn. Res.

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Nymphaea nouchali (Syn. Nymphaea stellata Willd.) from family Nymphaeaceae, is a species of perennial aquatic flowering plant with huge round floating leaves and rhizomes. It is well-known and prominent herb in Ayurveda and Siddha system of medicines with multiple medicinal properties. It comes from southern and eastern regions of Asia, and is a national blossom of Sri Lanka and Bangladesh. Scientific investigation has revealed that it exhibits vast range of pharmacological actions, namely antihyperglycemic, antioxidant, antimicrobial, analgesic, antiinflammatory, antipyretic, antitumor, hepatoprotective, antiulcer, antihelmintic, antinociceptive, immunomodulatory activities etc. Polyphenols, flavonoids, sterols, alkaloids, saponins, tannins, protein, nymphasterol, nymphayol have been recognized as important factors in the medicinal effects of N. nouchali. The present review focuses on pharmacological and phytochemical investigation of N. nouchali.

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Steroids from the stem of Nymphaea stellata

Cited by 6 publications

References 12 publications

Qualitative and quantitative determination of secondary metabolites and antioxidant potential of Nymphaea nouchali flowers

Qualitative and quantitative determination of secondary metabolites and antioxidant potential of Nymphaea nouchali flowers

Phytochemical analysis and In vitro antioxidant acitivity of hydroalcoholic seed extract of Nymphaea nouchali Burm. f.

Water Lily (Nymphaea nouchali Burm. f): An Ancient Treasure of Food and Medicine

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