Steroid-Resistant Late Acute Rejection after a Living Donor Liver Transplantation: Case Report and Review of the Literature

Post-transplantation lymphoproliferative disorder in living-donor liver transplantation: a single-center experience

“…Rejection episodes were treated with methylprednisolone pulse therapy. Deoxyspergualin [24] or murine monoclonal anti-CD3 antibody (OKT3) was given when steroid treatment failed.…”

Liver Biopsy After Liver Transplantation

“…The most common cause of early allograft dysfunction is acute cellular rejection (ACR). Although most cases of ACR occur in the first three months post-transplant (most often in the second or third post-transplant week), late-onset ACR (occurring up to 10 years post-transplant) has been reported [23]. ACR typically presents as moderate to severe elevations in hepatic transaminases and alkaline phosphatase/GGT, with some degree of bilirubin elevation, often in patients with a recent history of inadequate immunosuppression.…”