Steroid‐induced glaucoma treated with trabecular ablation in a matched comparison with primary open‐angle glaucoma

Abstract

Background:To evaluate the outcomes of trabectome-mediated ab interno trabeculectomy in patients with steroid-induced glaucoma (SIG).

Two-Year Outcomes of Ab Interno Trabeculectomy with the Trabectome for Chinese Primary Open Angle Glaucoma: A Retrospective Multicenter Study

“…Akil et al found that with similar preoperative values, IOP reduction in pigmentary glaucoma cases was similar to that in POAG [22]. In our previous studies, patients with pseudoexfoliative-and steroid-induced glaucoma with higher preoperative IOP finally obtained more IOP reduction than age-and gender-matched POAG controls [10,32,33]. Even though preoperative IOP was higher in these patients, the overall success rate was unchanged [10,22,34,35] or even better [34,36] than for POAG patients.…”

“…The Trabectome surgery was performed as we described previously [10,19]. IOP was measured by Goldmann applanation tonometry.…”

“…These procedures reduce IOP by different mechanisms: 1) ablate or bypass the trabecular meshwork (TM) using instruments such as the Trabectome (Neomedix Corporation, Tustin, CA, USA) [9][10][11], iStent (Glaukos Corp., Laguna Hills, CA, USA) [12], or the Hydrus mini-stent (Ivantis Inc., Irvine, CA, USA) [13]; 2) establish a new route for suprachoroidal drainage (CyPass Micro-Stent; Transcend Medical, Menlo Park, CA, USA [14]; 3) reduce the production of aqueous humor [15]; or 4) create a subconjunctival filtration route [16].…”

“…The Trabectome provides active irrigation and aspiration, which maintains better stability and temperature in the anterior chamber, compared with passive chamber management [18]. No hypotony or bleb-related complications occur [10,11,19,20].…”

“…However, in that study, we included different types of open-angle glaucomas, which might have different responses [10,22]. Also, the follow-up in that study was only 1 year.…”