Stereotactic radiosurgery using the gamma knife for acoustic neuromas

Foote, Robert L.; Coffey, Robert J.; Earle, John D.; Schomberg, Paula J.; Shaw, E.G.; Swanson, John W.; Davis, Deborah; Kelly, Patrick; Horner, Sherye D.; Beatty, Charles W.; Brey, Robin L.; Robinette, Michael; Bourland, Daniel; Kline, Robert W.; McCullough, Edwin C.; Stevens, Lorna N.; O’Fallon, Judith R.

doi:10.1016/0360-3016(93)90668-l

Cited by 137 publications

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“…Few authors report the use of serial imaging studies and clinical evaluations to determine outcomes and recurrence rates over time. [3,5,10,14,20,[23][24][25] There are no reports documenting clinical outcomes that include patient employment status and satisfaction. Detailed yet early assessments of the results after gamma knife radiosurgery have been published.…”

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confidence: 96%

“…Detailed yet early assessments of the results after gamma knife radiosurgery have been published. [3][4][5][6][7][20][21][22][23] Only preliminary information is available on results after radiosurgery for the management of neurofibromatosis Type 2 (NF2) tumors. [17] To define outcomes after acoustic neuroma radiosurgery, we studied all patients who underwent radiosurgery at a single center between 1987 and 1998.…”

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confidence: 99%

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Outcomes after gamma knife radiosurgery in solitary acoustic tumors and neurofibromatosis Type 2

Kondziolka¹,

Subach²,

Lunsford³

et al. 1998

FOC

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Surgeons perform stereotactic radiosurgery as the main alternative to acoustic tumor (vestibular schwannoma) resection. The goals of radiosurgery include preservation of neurological function and prevention of tumor growth. Longer-term outcomes are not well documented for patients with solitary tumors or those with neurofibromatosis Type 2 (NF2). To define outcomes, the authors evaluated 462 consecutive patients with solitary acoustic tumors and 40 patients with NF2 (total of 45 tumors treated) who underwent radiosurgery between 1987 and 1998. Serial imaging studies, clinical evaluations, and a patient survey were performed. The average tumor margin dose was 15 Gy, and the mean transverse tumor diameter was 22 mm. In patients with solitary tumors, prior resection had been performed in 111 patients (24%); 27 patients experienced tumor recurrence after a “total resection.” The clinical tumor control rate (no resection required) was 98%. In non-NF2 patients followed for at least 5 years, 100 tumors (61.7%) were smaller, 53 (32.7%) remained unchanged in size, and nine (5.6%) were slightly larger. Resection was performed in four patients (2.4%). Neurological deficits after radiosurgery all occurred within the first 28 months. The rates of facial and trigeminal neuropathy varied with radiosurgery technique. In patients with NF2, 16 tumors were smaller, 28 remained unchanged, and one enlarged (overall 98% control rate at median 3-year follow up). Resection was performed in three patients (7%). Useful hearing was preserved in six (43%) of 14 NF2 patients who had useful hearing before radiosurgery. Radiosurgery provided long-term tumor control associated with high rates of neurological function preservation. No further tumor surgery was necessary in 98% of patients with solitary tumors followed for a minimum of 5 years.

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confidence: 96%

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confidence: 99%

Outcomes after gamma knife radiosurgery in solitary acoustic tumors and neurofibromatosis Type 2

Kondziolka¹,

Subach²,

Lunsford³

et al. 1998

FOC

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“…Management strategies include close observation, surgical resection, and stereotactically guided radiosurgery. 1,4,8,9,11,13,15,26,36,49 Given the bilateral nature of the disease process, preservation of functional neurological status, particularly in regard to hearing, is of paramount importance. Several reports define the outcomes and morbidity resulting from surgical intervention for acoustic tumors in both sporadic and NF2-related cases.…”

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confidence: 99%

Stereotactic radiosurgery in the management of acoustic neuromas associated with neurofibromatosis Type 2

Subach

Kondziolka²,

Lunsford³

et al. 1999

Journal of Neurosurgery

114

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“…11,20 Experience with radiosurgery now extends more than 30 years. During the late 1980s and early 1990s, patients and their doctors chose radiosurgery or resection based mainly on early outcomes data derived from limited patient series.…”

Section: Stereotactic Radiosurgerymentioning

confidence: 99%

Comparison of management options for patients with acoustic neuromas

Kondziolka

Lunsford²,

Flíckinger³

2003

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Management options for patients with vestibular schwannomas (acoustic neuromas) include observation, tumor resection, stereotactic radiosurgery, and fractionated radiotherapy. In this report the authors review their 15-year experience with radiosurgery and discuss indications and expectations in relation to the different approaches. They conducted a survey of neurosurgeons to determine management preferences in two different cases of intra- and extra-canalicular tumor presentations. Patient decisions must be based on quality information derived from peer-reviewed literature.

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Stereotactic radiosurgery using the gamma knife for acoustic neuromas

Cited by 137 publications

References 0 publications

Outcomes after gamma knife radiosurgery in solitary acoustic tumors and neurofibromatosis Type 2

Outcomes after gamma knife radiosurgery in solitary acoustic tumors and neurofibromatosis Type 2

Stereotactic radiosurgery in the management of acoustic neuromas associated with neurofibromatosis Type 2

Comparison of management options for patients with acoustic neuromas

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