Stereotactic Radiosurgery for Brain Metastases from Human Epidermal Receptor 2 Positive Breast Cancer: An International, Multi-center Study
Stylianos Pikis,
Georgios Mantziaris,
Maria Protopapa
et al.
Abstract:Purpose
To report patient outcomes and local tumor control rates in a cohort of patients with biopsy-proven HER-2 positive breast cancer treated with stereotactic radiosurgery (SRS) for brain metastases (BM).
Methods
This international, retrospective, multicenter study, included 195 female patients with 1706 SRS-treated BM. Radiologic and clinical outcomes after SRS were determined and prognostic factors identified.
Results
At SRS, median patient age was 55 years [interquartile range (IQR) 47.6–62.0], and 1… Show more
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