Stereotactic radiosurgery for arteriovenous malformations after embolization: a case-control study

Kano, Hideyuki; Kondziolka, Douglas; Flickinger, John C.; Park, Kyung Jae; Iyer, Aditya; Yang, Huai Che; Liu, Xiaomin; Monaco, Edward A.; Niranjan, Ajay; Lunsford, L. Dade

doi:10.3171/2012.4.jns111935

Cited by 117 publications

(83 citation statements)

References 40 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Proper selection of patients undergoing radiosurgery is paramount in predicting success of radiosurgery. Multiple factors have been proposed as positive predictors for complete AVM obliteration such as the volume of AVM [10][11][12] and history of prior embolization [11,[13][14][15]. However, some inconsistencies exist in the literature.…”

Section: Introductionmentioning

confidence: 99%

“…Three studies [10][11][12] of 395 patients presented the OR of the relationship between higher target volume and obliteration rate. All of these studies suggested that a higher target volume was associated with lower the obliteration rate.…”

Section: Target Volumementioning

confidence: 99%

“…All of these studies suggested that a higher target volume was associated with lower the obliteration rate. Two studies [11,12] suggested the cutoff values of target volume at 4ml and 8ml. The pooled OR of higher target volume for obliteration was 0.82 (95% CI, 0.71-0.95, p = 0.009, Figure 1F) by a random-effects model (p = 0.14 and I 2 = 50%).…”

Section: Target Volumementioning

confidence: 99%

“…Six-hundred and seventy (670) unrelated articles were excluded. After reviewing the full texts of the 31 selected articles, 10 articles [10][11][12][13][14][15][16][19][20][21] met the inclusion criteria and where selected for the analysis. From the selected articles, 10 predictive factors were identified and subsequently analyzed, including rupture of AVM, deep location, noneloquence, craniotomy surgery, prior embolization, volume of AVM, max diameter, gender, age, and high margin dose.…”

Section: Literature Researchmentioning

confidence: 99%

See 3 more Smart Citations

WITHDRAWN: Predictors for complete obliteration of arteriovenous malformations following stereotactic radiosurgery

Ye¹,

Ai²,

Hu³

et al. 2017

Oncotarget

View full text Add to dashboard Cite

Conclusions: A previously ruptured AVM, a lower Spetzler-Martin grade, a higher marginal dose, non-deep location, no prior embolization, smaller target volume, and lower RBAS were identified as positive predictors for obliteration. Particularly, patients with AVM categorized as having a lower RBAS, radiosurgery should be considered as a first management option for a higher obliteration rate. However, factors such as age, eloquence and sex were not found to influence obliteration rates.

show abstract

Section: Introductionmentioning

confidence: 99%

Section: Target Volumementioning

confidence: 99%

Section: Target Volumementioning

confidence: 99%

Section: Literature Researchmentioning

confidence: 99%

See 2 more Smart Citations

WITHDRAWN: Predictors for complete obliteration of arteriovenous malformations following stereotactic radiosurgery

Ye¹,

Ai²,

Hu³

et al. 2017

Oncotarget

View full text Add to dashboard Cite

show abstract

“…41 It is noteworthy, however, that a number of reports indicate a negative association between successful AVM radiosurgical obliteration and previous embolization. [49][50][51][52] For this reason, employing a strategy of preradiosurgical embolization for the purpose of AVM volume reduction is controversial at best. 43 …”

Section: Preradiosurgical Embolizationmentioning

confidence: 99%

Role of Embolization for Cerebral Arteriovenous Malformations

Ellis

Lavine

2014

Methodist DeBakey Cardiovascular Journal

View full text Add to dashboard Cite

Volume staging for arteriovenous malformation SRS treatment using VMAT

Mendez

Gete²

2022

J Applied Clin Med Phys

View full text Add to dashboard Cite

Volume staging involves dividing the target volume into smaller parts and treating each part separately. In this study, the feasibility of volume‐staged stereotactic radiosurgery (VS‐SRS) on a linear accelerator using volumetric modulated arc therapy (VMAT) and a frameless patient positioning system is investigated. Ten patients, previously treated with hypofractionated stereotactic radiotherapy with arteriovenous malformation (AVM) sized from 1.6 to 4.0 cm in diameter, were selected. VS‐SRS plans were created with the VMAT technique on the Varian Eclipse treatment planning system (TPS) using the TrueBeam STx linear accelerator. For each patient, an AVM‐VMAT set was planned with the AVM as the target and a PTV‐VMAT set using the (PTV = AVM+1 mm) as the target. All targets were divided into two sub‐volumes. The TPS data from the AVM‐VMAT plans was compared to Gamma Knife (GK) VS‐SRS plan data available in the literature. The AVM‐VMAT and PTV‐VMAT plans were compared to investigate the effect of a 1 mm PTV margin on normal brain (NB) dose. End‐to‐end testing was performed using a GaFchromic EBT3 film and point‐dose measurements. Dosimetric effects of multiple setups were investigated through film‐to‐film comparisons. Median target dose coverage, NB V12Gy, and conformity index for the AVM‐VMAT plans were 97.5%, 17 cm3, and 0.8, respectively. PTV‐VMAT plans attained comparable target dose coverage, but the average NB V12Gy increased by 48.9% when compared to the AVM‐VMAT plans. Agreement of point‐dose measurements with TPS calculations was −0.6% when averaged over all patients. Gamma analysis passing rates were above 90% for all film‐to‐film comparisons (2%/1 mm criteria), and for the film to TPS comparison (5%/1 mm). This work suggests that VMAT is capable of producing VS‐SRS plans with similar dose falloff characteristics as GK plans. NB dose depends on PTV margin size, and two‐stage treatment setups do not appear to contribute additional uncertainty to treatment delivery.

show abstract

Stereotactic radiosurgery for arteriovenous malformations after embolization: a case-control study

Cited by 117 publications

References 40 publications

WITHDRAWN: Predictors for complete obliteration of arteriovenous malformations following stereotactic radiosurgery

WITHDRAWN: Predictors for complete obliteration of arteriovenous malformations following stereotactic radiosurgery

Role of Embolization for Cerebral Arteriovenous Malformations

Volume staging for arteriovenous malformation SRS treatment using VMAT

Contact Info

Product

Resources

About