Stereotactic LINAC radiosurgery for the treatment of typical intracranial meningiomas

El-Khatib, Mustafa; Majdoub, Faycal El; Hunsche, PD Stefan; Hoevels, Mauritius; Köcher, Martin; Sturm, Volker; Maarouf, PD Mohammad

doi:10.1007/s00066-015-0880-9

Cited by 18 publications

(21 citation statements)

References 42 publications

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“…The impact of tumor location on the tumor control was investigated by 4 studies. 18 , 20 , 22 , 33 Two out of these studies 22 , 33 suggest that parafalcine, parasagittal, and convexity locations are significant negative prognostic factors in terms of tumor control, while other 2 studies 18 , 20 did not observe statistical significance.…”

Section: Resultsmentioning

confidence: 98%

“…The longest reported observation period was 15 yr in one study with a PFS of 89%. 18 Eight- to ten-year PFS rates were reported in 10 studies 12 , 13 , 18 , 21 , 22 , 25 , 27 , 31 , 35 , 36 that evaluated more than 1146 patients, with a PFS rate ranging from 55% to 97% (median, 85.0%). Four- to five-year PFS rates ranged from 74% to 99% (median, 89.4%) in 14 studies, based on more than 1057 patients.…”

Section: Resultsmentioning

confidence: 99%

“…Amongst those reporting predictive factors, the most common factors associated with tumor control were smaller tumor volume 12 , 18 , 26 , 33 and patient age (lower than 65). 12 , 21 , 36 …”

Section: Resultsmentioning

confidence: 99%

“… 16 , 31 , 34 Two studies included both SRS and HSRT treatments; in these studies, 51 tumors had SRS and 60 tumors had HSRT. 20 , 29 The Gamma Knife (Elekta AB) was the reference device in 20 studies (3316 tumors), 11-15 , 17 , 19-23 , 25-28 , 30 , 32 , 33 , 35 , 36 the LINAC in 4 (231 tumors), 10 , 16 , 18 , 24 the CyberKnife (Accuray) in 2 (184 tumors), 29 , 31 and proton SRS in 1 study (19 tumors). 34 …”

Section: Resultsmentioning

confidence: 99%

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Stereotactic Radiosurgery for Intracranial Noncavernous Sinus Benign Meningioma: International Stereotactic Radiosurgery Society Systematic Review, Meta-Analysis and Practice Guideline

et al. 2020

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BACKGROUND Stereotactic radiosurgery (SRS) for benign intracranial meningiomas is an established treatment. OBJECTIVE To summarize the literature and provide evidence-based practice guidelines on behalf of the International Stereotactic Radiosurgery Society (ISRS). METHODS Articles in English specific to SRS for benign intracranial meningioma, published from January 1964 to April 2018, were systematically reviewed. Three electronic databases, PubMed, EMBASE, and the Cochrane Central Register, were searched. RESULTS Out of the 2844 studies identified, 305 had a full text evaluation and 27 studies met the criteria to be included in this analysis. All but one were retrospective studies. The 10-yr local control (LC) rate ranged from 71% to 100%. The 10-yr progression-free-survival rate ranged from 55% to 97%. The prescription dose ranged typically between 12 and 15 Gy, delivered in a single fraction. Toxicity rate was generally low. CONCLUSION The current literature supporting SRS for benign intracranial meningioma lacks level I and II evidence. However, when summarizing the large number of level III studies, it is clear that SRS can be recommended as an effective evidence-based treatment option (recommendation level II) for grade 1 meningioma.

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Section: Resultsmentioning

confidence: 98%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

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Stereotactic Radiosurgery for Intracranial Noncavernous Sinus Benign Meningioma: International Stereotactic Radiosurgery Society Systematic Review, Meta-Analysis and Practice Guideline

et al. 2020

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“…During the past two decades, SRT has become increasingly well known as a treatment option for meningiomas (16, 17). Adjuvant SRT is offered to all grades II and III meningioma patients, whereas symptomatic grade I meningioma patients only received SRT after incomplete resection.…”

Section: Methodsmentioning

confidence: 99%

Electronic Support for Retrospective Analysis in the Field of Radiation Oncology: Proof of Principle Using an Example of Fractionated Stereotactic Radiotherapy of 251 Meningioma Patients

et al. 2017

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IntroductionThe purpose of this study is to verify the possible benefit of a clinical data warehouse (DWH) for retrospective analysis in the field of radiation oncology.Material and methodsWe manually and electronically (using DWH) evaluated demographic, radiotherapy, and outcome data from 251 meningioma patients, who were irradiated from January 2002 to January 2015 at the Department of Radiation Oncology of the Erlangen University Hospital. Furthermore, we linked the Oncology Information System (OIS) MOSAIQ® to the DWH in order to gain access to irradiation data. We compared the manual and electronic data retrieval method in terms of congruence of data, corresponding time, and personal requirements (physician, physicist, scientific associate).ResultsThe electronically supported data retrieval (DWH) showed an average of 93.9% correct data and significantly (p = 0.009) better result compared to manual data retrieval (91.2%). Utilizing a DWH enables the user to replace large amounts of manual activities (668 h), offers the ability to significantly reduce data collection time and labor demand (35 h), while simultaneously improving data quality. In our case, work time for manually data retrieval was 637 h for the scientific assistant, 26 h for the medical physicist, and 5 h for the physician (total 668 h).ConclusionOur study shows that a DWH is particularly useful for retrospective analysis in the radiation oncology field. Routine clinical data for a large patient group can be provided ready for analysis to the scientist and data collection time can be significantly reduced. Furthermore, linking multiple data sources in a DWH offers the ability to improve data quality for retrospective analysis, and future research can be simplified.

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Perioptic Meningiomas

Fariselli¹,

Pinzi²,

Morlino³

et al. 2020

CyberKnife NeuroRadiosurgery

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Stereotactic LINAC radiosurgery for the treatment of typical intracranial meningiomas

Cited by 18 publications

References 42 publications

Stereotactic Radiosurgery for Intracranial Noncavernous Sinus Benign Meningioma: International Stereotactic Radiosurgery Society Systematic Review, Meta-Analysis and Practice Guideline

Stereotactic Radiosurgery for Intracranial Noncavernous Sinus Benign Meningioma: International Stereotactic Radiosurgery Society Systematic Review, Meta-Analysis and Practice Guideline

Electronic Support for Retrospective Analysis in the Field of Radiation Oncology: Proof of Principle Using an Example of Fractionated Stereotactic Radiotherapy of 251 Meningioma Patients

Perioptic Meningiomas

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