Stereotactic intracavitary brachytherapy with P-32 for cystic craniopharyngiomas in children

Maarouf, PD Mohammad; Majdoub, Faycal El; Fuetsch, Manuel; Hoevels, Mauritius; Lehrke, Ralph; Berthold, Frank; Voges, Jürgen; Sturm, Volker

doi:10.1007/s00066-015-0910-7

Cited by 16 publications

(10 citation statements)

References 42 publications

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“…However, several studies have documented the efficacy of intracystic therapy including bleomycin and interferon‐alpha, in both the upfront and recurrent settings 93‐95 . In addition, intracavitary radionuclides, including yttrium‐90 and phosphorus‐32, have demonstrated efficacy 96‐98 …”

Section: Craniopharyngiomasmentioning

confidence: 99%

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Gliomas, germ cell tumors, and craniopharyngioma

Aridgides

Janssens

Braunstein

et al. 2020

Pediatric Blood & Cancer

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This report summarizes the current multimodality treatment approaches for children with low‐ and high‐grade gliomas, germinoma, and nongerminomatous germ cell tumors, and craniopharyngiomas used in the Children's Oncology Group (COG) and the International Society of Pediatric Oncology (SIOP). Treatment recommendations are provided in the context of historical approaches regarding the roles of surgery, radiation, and chemotherapy. Future research strategies for these tumors in both COG and SIOP are also discussed.

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Section: Craniopharyngiomasmentioning

confidence: 99%

“…[93][94][95] In addition, intracavitary radionuclides, including yttrium-90 and phosphorus-32, have demonstrated efficacy. [96][97][98]…”

Section: Role Of Chemotherapymentioning

confidence: 99%

Gliomas, germ cell tumors, and craniopharyngioma

Aridgides

Janssens

Braunstein

et al. 2020

Pediatric Blood & Cancer

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“…Treatment is mainly through surgical resection. Several surgical approaches have been developed depending on topographical location of the tumor, 1,4,[10][11][12] and post neuroendoscopy radiotherapy, 13 Gamma Knife surgery, 14,15 and occasional use of Ommaya reservoir placement, 16,17 proton beam therapy, 18,19 and intracavitary β-irradiation 20,21 have been reported in literature.…”

Section: Introductionmentioning

confidence: 99%

Pathological and Topographical Classification of Craniopharyngiomas: A Literature Review

Lubuulwa

Lei

2016

J Neurol Surg Rep

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Craniopharyngiomas (CPs) are clinically relevant tumors of the sellar region and are associated with high morbidity and occasional mortality. There are two different subtypes of CPs that differ clinically and pathologically: adamantinomatous CP and papillary CP. The differential diagnosis is still challenging even with developments in preoperative imaging as several tumors of the sellar/parasellar region share a continuum of clinical characteristics and imaging similarities. Several topographical classifications of CPs have been mentioned in literature, but to date, there has not been a consensus on a standard reference classification system and there is need to a develop such a model.

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“…While recurrent craniopharyngiomas are treated by resection, radiotherapy or radiosurgery, tumors with unresponsive cystic component can be treated by administration of P32, bleomycin or interferon alpha directly into the tumor bed. It can be supplemented by systemic administration of interferon [85].…”

Section: Craniopharyngiomamentioning

confidence: 99%

Primary Brain Tumors in Childhood

Richterová¹,

Kolarovszki²

2018

Brain Tumors - An Update

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This chapter offers literary review of most frequently observed brain tumors in childhood. It offers basics of epidemiology, clinical presentation and diagnostics of most often occurring types of tumors according to new WHO classification of brain tumors from 2016 and emphasizes molecular biological characteristics and role of altered genes and genetic pathways in brain tumor etiology, classification and treatment. This review not only concentrates on gliomas, medulloblastomas and ependymomas, but also offers characterization of other less frequently observed lesions. Each tumor characteristics also contains basics of therapeutical possibilities of these lesions with focus on targeted and individually designed therapy according to molecular and genetic alterations found in tumor tissue sample.

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Stereotactic intracavitary brachytherapy with P-32 for cystic craniopharyngiomas in children

Abstract: Intracavitary brachytherapy using P-32 represents a safe and effective treatment option for children harboring cystic CP, even as primary treatment. However, P-32 does not clearly affect growth of solid tumor parts or the development of new cystic formations.

Cited by 16 publications

References 42 publications

Gliomas, germ cell tumors, and craniopharyngioma

Gliomas, germ cell tumors, and craniopharyngioma

Pathological and Topographical Classification of Craniopharyngiomas: A Literature Review

Primary Brain Tumors in Childhood

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