Stereotactic core breast biopsy of a minimal carcinoma complicated by a large hematoma: a management dilemma.

Deutch, B M; Schwartz, Mitchell; Fodera, T; Ray, David M.

doi:10.1148/radiology.202.2.9015069

Cited by 15 publications

(6 citation statements)

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“…In addition, in a small Bleeding Risk After Core Needle Breast Biopsy preliminary study, Melotti and Berg [10] reported 18 patients on anticoagulant ther apy who underwent 14 or 11gauge biopsy without clinically important complications and a hematoma rate similar to that of the nonanticoagulated control group. In a single study, Deutch and colleagues [11] described a small carcinoma that was obscured by a large hematoma that resulted from biopsy, which delayed surgical excision by 12 weeks. In our experience, core needle biopsy, whether performed using stereotactic, sono graphic, or MRI guidance, with a variety of needle sizes ranging from 14 to 9gauge can be performed safely on patients taking daily aspirin or therapeuticallyinrange warfarin.…”

Section: Discussionmentioning

confidence: 99%

Anticoagulation and Bleeding Risk After Core Needle Biopsy

Somerville¹,

Seifert²,

Destounis³

et al. 2008

American Journal of Roentgenology

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Section: Discussionmentioning

confidence: 99%

Anticoagulation and Bleeding Risk After Core Needle Biopsy

Somerville¹,

Seifert²,

Destounis³

et al. 2008

American Journal of Roentgenology

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“…In our study, three patients developed a large hematoma after core biopsy; however, none required surgical evacuation. This complication can be detrimental, as it can obscure a small carcinoma at subsequent preoperative radiologic localization (20). Other limitations include malignant seeding along a core biopsy needle track (21) and total excision of a small lesion by the core needle (19).…”

Section: Discussionmentioning

confidence: 99%

The Use of Stereotaxic Core Biopsy and Stereotaxic Aspiration Biopsy as Diagnostic Tools in the Evaluation of Mammary Calcification

Cangiarella

Waisman

Weg³

et al. 2000

The Breast Journal

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We compared stereotaxic fine needle aspiration biopsy (SFNA) with stereotaxic core needle biopsy (SCB) in the evaluation of radiographically clustered mammary microcalcification, a common finding at screening mammography. Over a 4-year period, 181 specimens were obtained from 175 patients who underwent both SFNA and SCB of clustered microcalcification. Aspiration and core biopsies were performed by radiologists at a community-based diagnostic radiology facility. All aspiration smears were air dried, stained on site, and assessed for adequacy by the radiologists, then sent to the cytopathologists at New York University for interpretation. Core biopsy specimens were formalin fixed, paraffin embedded, hematoxylin and eosin stained, and interpreted by surgical pathologists at a community hospital. Of 181 SFNA specimens, 133 (74%) were benign, 18 (10%) were atypical, 13 (7%) were suspicious, and 16 (9%) were malignant. One (0.5%) aspiration biopsy was nondiagnostic. Excisional biopsies were performed after 12 benign SFNAs and in 46 of the 47 cases with an atypical, suspicious, or malignant diagnosis on SFNA. Mammographic follow-up in 111 of the 133 cases (92%) diagnosed as benign showed no radiologic change (mean 29.2 months, range 6-60 months). The false-negative rate for cancer was 4% (6 cases) for SFNA alone. There were no false-positive diagnoses for SFNA. There was one false-positive diagnosis on core biopsy [focal cribriform ductal carcinoma in situ (DCIS)], which at excisional biopsy and correlation with the core biopsy was diagnosed as ductal hyperplasia; the false-negative rate for cancer was 8% (13 cases) for SCB alone. Aspiration biopsy identified calcification in 180 procedures, core needle biopsy revealed calcification in 170. SFNA was superior to SCB for the confirmation of clustered mammary microcalcification (99% versus 94%) and in the identification of cancer associated with microcalcification (false negative rate of 4% versus 8%). Patients with benign findings on stereotaxic aspiration and core biopsy can reasonably be followed mammographically.

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“…The bleeding controls for routing and extended biopsy and surgical procedures have presented some levels of risk. 43 We have attempted to compare a novel process with the use of a commercial product "Instant Clot Pad" (Bio-Sponge Technology Co., Ltd., Taiwan), a chitosam polymer material preparation, to the standard process with ordinary cotton dressing. The "Instant Clot Pad" is a spongy-like porous material with average pore size about 200-250 µm.…”

Section: Chitosan As Rapid Clotting Wound Dressmentioning

confidence: 99%

Chitosan in Applications of Biomedical Devices

Lan

Niu

Chang

et al. 2011

Biomed. Eng. Appl. Basis Commun.

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Chitosan is a natural polysaccharide with great potential for biomedical applications due to its biocompatibility, biodegradable capability, and nontoxicity. Various techniques used for preparing chitosan microspheres/membranes and evaluations of these fabrications have also been reviewed. The hydrophilicity of chitosan provides unique characteristics of hydrogel formation with the acidic media and may entrap the drug content inside of the matrix for controlled release. In order to improve upon the scope of preparation of chitosan microspheres, we had successfully employed and incorporated a high-voltage system into the direct pumping injection process. The wide range of drug release profiles could be attributed to the surface characteristics, porosities, and various structures of chitosan microspheres upon treatment with Na5P3O10/NaOH solutions of various volume ratios. We also demonstrated that with the addition of chitosan/β-TCP microspheres as a constituent into the PMMA cement significantly decreases the curing peak temperature and increases the setting time. The excellent gelforming property of chitosan offers another biomedical application in membrane separation fields. Chitosan membranes were prepared by a thermal induced phase separation method, following treatment with nontoxic NaOH gelating and Na5P3O10, Na2SO3 crosslinking agents. In order to further improve the mechanical strength and biocompatibility and to expand the potential of chitosan GTR membranes in periodontal applications, various chitosan membranes incorporating with negatively charged alginate, bioactive tricalcium phosphate, and platelet rich plasma, respectively, were also prepared and characterized. Moreover, we had also utilized chitosan, which with good blood-clotting, cheap, and easy preparation characteristics, as the raw material to prepare rapid clotting wound dressing and tooth plug.

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Stereotactic core breast biopsy of a minimal carcinoma complicated by a large hematoma: a management dilemma.

Cited by 15 publications

References 0 publications

Anticoagulation and Bleeding Risk After Core Needle Biopsy

Anticoagulation and Bleeding Risk After Core Needle Biopsy

The Use of Stereotaxic Core Biopsy and Stereotaxic Aspiration Biopsy as Diagnostic Tools in the Evaluation of Mammary Calcification

Chitosan in Applications of Biomedical Devices

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