Stereotactic Computed Tomography-guided Biopsy of Brainstem Lesions

Meshkini, Ali; Shahzadi, Sohrab; Zali, Alireza; Parsa, Khosro; Afrough, Aimaz; Hamdi, Amir

doi:10.1097/wnq.0b013e31823450b9

Cited by 1 publication

(2 citation statements)

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Section: Discussionmentioning

confidence: 99%

“…[20] Furthermore, in a study about stereotactic biopsy of brain stem lesions we reported a large number of patients with multiple lesions involving brain stem that histopathologic examinations revealed glioblastoma multiform anaplastic astrocytoma, lymphoma, abscess, adenocarcinoma, and multiple sclerosis. [21] Therefore, patients with multiple cerebral space-occupying lesions can be categorized into two groups: A. Patients without previous history of tumor who had multiple SOLs: These patients should be analyzed thoroughly since, they are suspected to have malignancy in other parts of their bodies.…”

Section: Discussionmentioning

confidence: 99%

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Role of stereotactic biopsy in histological diagnosis of multiple brain lesions

Meshkini

Shahzadi²,

Alikhah

et al. 2013

Asian J Neurosurg

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Background and Aim:The current advances in diagnostic and therapeutic modalities and increasing in survival of patients with systemic diseases and immunosuppressive cases have caused to increasing frequency and variety of Central Nervous System neuropathologic processes indicating the necessary need for accurate localization of space-occupying lesions by cytology and histology. This study was aimed to evaluate the usefulness and safety of stereotactic biopsy in histological diagnosis of such lesions.Materials and Methods:Of 2081 patients underwent stereotactic biopsy of brain lesions using Riechert-Mundinger system, 158 had multifocal brain lesions, and were enrolled.Results:The ages of studied cases were ranged from 2 years to 75 years (Mean age: 41.3 year), 114 were male and 44 were females. Incidence of histopathologic diagnosis of multifocal brain lesions included Astrocytoma grade II (41.3%), Astrocytoma grade I (12.9%), glioblastoma multiform (11.1%), Astrocytoma grade III (10.2%), malignant lymphoma (10.2%), metastasis (4.6%), pilocytic Astrocytoma (2.7%), abscess (2.7%), craniopharyngioma (1.8%) vascular malformations (0.9%), and tuberculosis (0.9%). Mortality due to operation is none.Conclusions:Histopathologic diagnosis of multiple brain lesions is necessary for decision of appropriate management and stereotactic biopsy of brain lesion is a useful and safe method for histological diagnosis.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%