Stereotactic Body Radiation Therapy for Patients with Early-stage Prostate Cancer

Linney, H.; Barrett, Sarah

doi:10.21873/anticanres.12344

Cited by 1 publication

(1 citation statement)

References 32 publications

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“…Compared with salvage HIFU, SRT has different complications in patients with recurrent PCa after RP. The side effects of radiotherapy for PCa mainly include gastrointestinal (GI) toxicity, genitourinary (GU) toxicity, Erectile dysfunction (ED) and myelosuppression (19). Lisanne et al reported long-term treatment toxicity and urinary incontinence rate after radical prostatectomy using SRT.…”

Section: Different Side Effects Between Hifu and Radiotherapy As Salvage Therapy For Recurrent Pcamentioning

confidence: 99%

The Use of High-Intensity Focused Ultrasound (HIFU) Plus 150mg Bicalutamide as First Line Salvage Therapy for Local Recurrent Prostate Cancer

Cao

Pan

et al. 2021

Front. Oncol.

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Patients with localized prostate cancer (PCa) are often treated with radical prostatectomy (RP). However, more than 30% of such patients have high risk of recurrence. Salvage radiotherapy (SRT), androgen deprivation therapy (ADT) and combination of radiotherapy and ADT are the standard care for recurrent PCa. Recently, high intensity focused ultrasound (HIFU) has gradually applied in the treatment of recurrent PCa. Here, we proposed a hypothesis that combined HIFU and bicalutamide 150mg as first line salvage therapy to treat patients with local recurrent PCa with visible lesions due to the following advantages: (1) HIFU is effective in reducing local tumor load, and bicalutamide 150mg is a feasible and safety option to combine with HIFU. (2) Compared with radiotherapy, HIFU plus 150mg bicalutamide is minimal invasiveness with fewer adverse effects and better quality of life(QOL); (3) Radiotherapy can be preserved as the second-line salvage method in the cases who are failure to HIFU and 150mg bicalutamide combination. More clinical trials are warranted to confirm this hypothesis in treatment with recurrent PCa.

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Section: Different Side Effects Between Hifu and Radiotherapy As Salvage Therapy For Recurrent Pcamentioning

confidence: 99%

The Use of High-Intensity Focused Ultrasound (HIFU) Plus 150mg Bicalutamide as First Line Salvage Therapy for Local Recurrent Prostate Cancer

Cao

Pan

et al. 2021

Front. Oncol.

View full text Add to dashboard Cite

show abstract

Stereotactic Body Radiation Therapy for Patients with Early-stage Prostate Cancer

Cited by 1 publication

References 32 publications

The Use of High-Intensity Focused Ultrasound (HIFU) Plus 150mg Bicalutamide as First Line Salvage Therapy for Local Recurrent Prostate Cancer

The Use of High-Intensity Focused Ultrasound (HIFU) Plus 150mg Bicalutamide as First Line Salvage Therapy for Local Recurrent Prostate Cancer

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