2023
DOI: 10.1016/j.ajur.2021.12.004
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Stereotactic ablative body radiotherapy for oligometastatic inguinal lymph node in castrate resistant prostate cancer

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Cited by 1 publication
(2 citation statements)
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“…We speculate that although higher grade tumors are more likely to metastasize, that does not necessarily mean that they will spread to atypical locations. Inguinal LN metastases were seen throughout grade groups 1–5 in our study, as has been described in case reports ( 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 ) . In two cohorts of patients with predominantly high-grade group PCa who underwent dissection of pelvic LNs, metastasis in deep inguinal LNs was confirmed on pathology in only one (2.6%) and three (1.1%) of the 39 and 285 patients in each cohort, respectively ( 28 , 29 ) .…”
Section: Discussionsupporting
confidence: 89%
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“…We speculate that although higher grade tumors are more likely to metastasize, that does not necessarily mean that they will spread to atypical locations. Inguinal LN metastases were seen throughout grade groups 1–5 in our study, as has been described in case reports ( 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 ) . In two cohorts of patients with predominantly high-grade group PCa who underwent dissection of pelvic LNs, metastasis in deep inguinal LNs was confirmed on pathology in only one (2.6%) and three (1.1%) of the 39 and 285 patients in each cohort, respectively ( 28 , 29 ) .…”
Section: Discussionsupporting
confidence: 89%
“…Recently, Schiller et al ( 4 ) investigated 799 LNs in 233 patients who underwent prostatespecific membrane antigen positron-emission tomography/computed tomography (PSMA PET/CT) and found that 10 inguinal LNs (1.3%) were suspicious (i.e., “PET-positive”), although there was again no verification by pathology. The remainder of the literature consists of a few case reports in which investigators raise hypotheses on potential pathways for the spread to inguinal LNs, such as altered lymphatic drainage after prostatectomy ( 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 ) . In clinical practice, questions regarding abnormal inguinal LNs raising concern for metastases are becoming increasingly common, especially with the growing popularity of molecular imaging (e.g., PSMA PET/CT).…”
Section: Introductionmentioning
confidence: 99%