Stereospecific ligands and their complexes. VI. The crystal structure of (S,S)-ethylenediamine-N,N'-di-2-propanoic acid hydrochloride, (S,S)-H2eddp•HCl

Abstract

S,S)-Ethylenediamine-N,N'-di-2-propanoic acid hydrochloride, (S,S)-H 2 eddp·HCl, was prepared and its crystal structure determined. The compound was characterized by infrared and 1 H-and 13 C-NMR spectroscopy. It forms P1 in the space group of a triclinic crystal system with a = 5.3902(2) Å, b = 5.8967(2) Å, c = 10.3319(2) Å, α = 99.625(2)°, β = 91.645(2)°, γ = = 109.995(2)° and Z = 1.

Synthesis and high in vitro cytotoxicity of some (S,S)-ethylenediamine-N,N’-di-2-propanoate dihydrochloride esters

“…In the reaction of (S,S)-ethylenediamine-N,N′-di-2-propanoic acid hydrochloride, (S,S)-H 2 eddip·HCl (crystal structure was described recently), 37 with absolute isopentyl alcohol (3-methyl-1-butanol) in the presence of thionyl chloride, diisopentyl (S,S)-ethylenediamine-N,N′-di-2-propanoate dihydrochloride (1) was obtained (Scheme 1). Scheme 1.…”