Stereospecific ligands and their complexes. V. Synthesis, characterization and antimicrobial activity of palladium(II) complexes with some alkyl esters of (S,S)-ethylenediamine-N,N′-di-2-propanoic acid

Synthesis and high in vitro cytotoxicity of some (S,S)-ethylenediamine-N,N’-di-2-propanoate dihydrochloride esters

“…22,23,28 A strong absorption stretching band ν(C=O) was found at 1733 cm −1 , while a band arising from ν(C−O) appeared at 1236 cm −1 . 22,23,28 A strong absorption stretching band ν(C=O) was found at 1733 cm −1 , while a band arising from ν(C−O) appeared at 1236 cm −1 .…”

Part XVI - Stereospecific ligands and their complexes. Synthesis, characterization and in vitro antiproliferative activity of new platinum(IV) complexes with some O,O'-dialkyl esters of (S,S)-ethylenediamine-N,N'-di-2-propanoic acid against breast cancer

“…The infrared spectra of the complexes confirmed the expected N-N coordination of the ligands to the platinum(IV) ion. Coordination via nitrogen ligand atoms could be proven by the presence of bands for secondary amino groups (3128 cm -1 for C1, 3125 cm -1 for C2, 3119 cm -1 for C3, and 3118 for C4) and absence of the protonated secondary ammonium group, found in the IR spectra of the R 2 -S,S-eddp precursors (3437 cm -1 for C1, 3461 cm -1 for C2, 3461 cm -1 for C3 and 3462 cm -1 for C4) [20,21]. The position and number of signals in the 1 H and 13 C NMR spectra for the isolated complexes confirmed the coordination of the esters to the platinum(IV) ion.…”

“…(S,S)-ethylenediamine-N,N'-di-2-propanoic acid (H 2 -S,S-eddp) was prepared [19] and esterified as previously described [20,21]. Where required, distilled water was used.…”

Carbohydrate triazole tethered 2-pyridyl-benzimidazole ligands: Synthesis of their palladium (II) complexes and antimicrobial activities

“…However, as a consequence of the rapid hydrolysis in aqueous solutions and lower bioactivity of palladium complexes, an appropriate ligand system which can sustain the biological environment is required [20]. Several palladium complexes with different nitrogen ligands have been designed for biological applications [21][22][23][24][25][26][27][28][29][30][31][32][33].…”