Stereology: a novel technique for rapid assessment of liver volume

Torkzad, Michael R.; Norén, Agneta; Kullberg, Joel

doi:10.1007/s13244-012-0166-z

Cited by 10 publications

(11 citation statements)

References 20 publications

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“…Volume assessment of liver and its segment can be measured by the technique called “volumetry.” This technique calculates the volume from the drawing contour of the interpolated liver images obtained by MDCT or MRI . The summation of volume from multiple segments can be further calculated for drainage purpose based on the anatomy of main duct.…”

Section: Consensus Statementsmentioning

confidence: 99%

Asia–Pacific consensus recommendations for endoscopic and interventional management of hilar cholangiocarcinoma

Rerknimitr

Angsuwatcharakon

Ratanachu‐ek³

et al. 2013

J of Gastro and Hepatol

220

171

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Hilar cholangiocarcinoma (HCCA) is one of the most common types of hepatobiliary cancers reported in the world including Asia-Pacific region. Early HCCA may be completely asymptomatic. When significant hilar obstruction develops, the patient presents with jaundice, pale stools, dark urine, pruritus, abdominal pain, and sometimes fever. Because no single test can establish the definite diagnosis then, a combination of many investigations such as tumor markers, tissue acquisition, computed tomography scan, magnetic resonance imaging/magnetic resonance cholangiopancreatography, endoscopic ultrasonography/intraductal ultrasonography, and advanced cholangioscopy is required. Surgery is the only curative treatment. Unfortunately, the majority of HCCA has a poor prognosis due to their advanced stage on presentation. Although there is no survival advantage, inoperable HCCA managed by palliative drainage may benefit from symptomatic improvement. Currently, there are three techniques of biliary drainage which include endoscopic, percutaneous, and surgical approaches. For nonsurgical approaches, stent is the most preferred device and there are two types of stents i.e. plastic and metal. Type of Declarations of conflict of interest: All authors have nothing to disclose.Author contributions: RR was involved with the consensus concept and design, acquisition of data, drafting of the manuscript, critical revision of the manuscript, obtain funding, and participation in electronic and face-to-face voting. PA and TR were involved with the consensus concept and design, acquisition of data, drafting of the manuscript, critical revision of the manuscript, and participation in electronic and face-to-face voting. CK, RP, JM, DS, LP, AS, PP, TA, DR, AM, SP, PK, MR, and MK were involved with drafting of the manuscript, critical revision of the manuscript, and participation in electronic and face-to-face voting. TI was involved with drafting of the manuscript, critical revision of the manuscript, and participation in electronic voting. NP, ST, SA, BD, HW, EO, DL, and PM were involved with critical revision of the manuscript, and participation in electronic and face-to-face voting. KG and BO were involved with critical revision of the manuscript and participation in electronic voting. SC and AJ were involved with study supervision and participation in electronic voting. VB was involved with study supervision. and number of stent for HCCA biliary drainage are subjected to debate because the decision is made under many grounds i.e. volume of liver drainage, life expectancy, expertise of the facility, etc. Recently, radio-frequency ablation and photodynamic therapy are promising techniques that may extend drainage patency. Through a review in the literature and regional data, the Asia-Pacific Working Group for hepatobiliary cancers has developed statements to assist clinicians in diagnosing and managing of HCCA. After voting anonymously using modified Delphi method, all final statements were determined for the level of evidence qual...

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Section: Consensus Statementsmentioning

confidence: 99%

Asia–Pacific consensus recommendations for endoscopic and interventional management of hilar cholangiocarcinoma

Rerknimitr

Angsuwatcharakon

Ratanachu‐ek³

et al. 2013

J of Gastro and Hepatol

220

171

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“…So the volume data is closer to the real data of a model when the interval of the scan image is smaller. But, if the number of image is larger, it will take a longer time to segment object region from medical images, and the cost of image scanning will increase [11]. The volume measurement method proposed in this paper will not be affected by the interval of the scan image, if the interval of the scan image is greater, interpolation method can be used for 3D reconstruction [22,23], that can optimally approximate the shape of 3D model and get more accurate volume data.…”

Section: Discussionmentioning

confidence: 99%

“…In addition, stereology method [11] is always used to calculate the area of object region approximately and get the volume of tissues and organs using volume integral method. In paper [11], a piece of abdominal image is divided into a lot of rectangular grids, the area of the liver region is achieved by counting the number of grids which are contained in liver region.…”

Section: Introductionmentioning

confidence: 99%

“…In paper [11], a piece of abdominal image is divided into a lot of rectangular grids, the area of the liver region is achieved by counting the number of grids which are contained in liver region. The above two volume measurement methods are based on different area calculation methods, but the core idea of the two methods is volume integral method.…”

Section: Introductionmentioning

confidence: 99%

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The study and implementation of liver volume measuring method based on 3-dimensional reconstruction technology

Ren

et al. 2015

Optik

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“…Different techniques can be used to estimate liver volume in vivo (Kayaalp et al, 2002;Luccichenti et al, 2003;Emirzeoglu et al, 2005;Muller et al, 2010;Torkzad et al, 2012;Aoyama et al, 2013). Advancements in radiological techniques have enabled the acquisition of MDCT images with fairly high temporal and spatial resolutions, which may be applied in accurate preoperative assessment of the resected liver volume and future liver remnant volume by CT volumetry.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Computer-Assisted Quantitative Volumetric Analysis for Pre-Operative Resectability Assessment of Huge Hepatocellular Carcinoma

Tang

Yan²,

Zhou³

et al. 2013

Asian Pacific Journal of Cancer Prevention

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Purpose: Hepatic resection is arguably the preferred treatment for huge hepatocellular carcinoma (H-HCC). Estimating the remnant liver volume is therefore essential. This study aimed to evaluate the feasibility of using computer-assisted volumetric analysis for this purpose. Methods: The study involved 40 patients with H-HCC. Laboratory examinations were conducted, and a contrast CT-scan revealed that 30 cases out of the participating 40 had single-lesion tumors. The remaining 10 had less than three satellite tumors. With the consensus of the team, two physicians conducted computer-assisted 3D segmentation of the liver, tumor, and vessels in each case. Volume was automatically computed from each segmented/labeled anatomical field. To estimate the resection volume, virtual lobectomy was applied to the main tumor. A margin greater than 1 cm was applied to the satellite tumors. Resectability was predicted by computing a ratio of functional liver resection (R) as (VresectedVtumor)/(Vtotal-Vtumor) x 100%, applying a threshold of 50% and 60% for cirrhotic and non-cirrhotic cases, respectively. This estimation was then compared with surgical findings. Results: Out of the 22 patients who had undergone hepatectomies, only one had an R that exceeded the threshold. Among the remaining 18 patients with non-resectable H-HCC, 12 had Rs that exceeded the specified ratio and the remaining 6 had Rs that were < 50%. Four of the patients who had Rs less than 50% underwent incomplete surgery due to operative findings of more extensive satellite tumors, vascular invasion, or metastasis. The other two cases did not undergo surgery because of the high risk involved in removing the tumor. Overall, the ratio of functional liver resection for estimating resectability correlated well with the other surgical findings. Conclusion: Efficient pre-operative resectability assessment of H-HCC using computer-assisted volumetric analysis is feasible.

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Stereology: a novel technique for rapid assessment of liver volume

Cited by 10 publications

References 20 publications

Asia–Pacific consensus recommendations for endoscopic and interventional management of hilar cholangiocarcinoma

Asia–Pacific consensus recommendations for endoscopic and interventional management of hilar cholangiocarcinoma

The study and implementation of liver volume measuring method based on 3-dimensional reconstruction technology

Evaluation of Computer-Assisted Quantitative Volumetric Analysis for Pre-Operative Resectability Assessment of Huge Hepatocellular Carcinoma

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