Stereological and behavioural analysis reveals the better neuroprotective effect of cinnamaldehyde than berberine chloride in a rat model of global cerebral ischemia
Dariush Mehboodi,
Abbas Shahedi,
Mohammadreza Namavar
et al.
Abstract:BackgroundGlobal cerebral ischemia (GCI) is characterized by the hindrance of blood flow to the brain due to obstruction in the carotid arteries. In this study, the neuroprotective effects of berberine chloride (BBR) and cinnamaldehyde (CA) against GCI in male Wistar rats were investigated, and their efficacy was compared.MethodsTwenty‐four rats were randomly assigned to four groups: Sham, GCI, GCI + BBR, and GCI + CA. 100 mg/kg of BBR and CA were administered five minutes and six hours after inducing GCI by o… Show more
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