Stereocontrolled Synthesis of All Eight Stereoisomers of the Putative anti‐Androgen Cyoctol.

Mulzer, Johann; Kaselow, Ulrich; Graske, Klaus-Dieter; Kuehne, H.; Sieg, Andreas; Martin, Harry J.

doi:10.1002/chin.200503085

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Therapeutic Agents For Alopecia1

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2013

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“…In addition, biphenyl compounds were found potently against 5α‐reductase type II at a low concentration . Despite there are several patents claim on alopecia treatment by syntheses and application of anti‐androgen agents, biological clarifications are needed because contrary results were indicated …”

Section: Therapeutic Agents For Alopeciamentioning

confidence: 99%

Hair loss and herbs for treatment

Lourith

Kanlayavattanakul

2013

J of Cosmetic Dermatology

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or androgenetic alopecia directly distresses self-confidence affecting the individual's quality of life. Hair loss is therefore a significant psychosocial manifestation that worth much expense on treatment. Androgenetic alopecia is noticed as a slow transformation of large scalp terminal hair follicles to shorter, thinner, and less deep vellus hair with a much shorter anagen. Although minoxidil, finasteride, and dutasteride including other synthetic therapeutic agents are mostly used for alopecia treatment, their adverse effects encourage sorting of alternative efficient treatment agent with a limited side effect particularly herbs. Thus, this review briefly summarized causes of hair loss and emphasized on active ingredients for treatment in particular currently used herbs and the potential candidates. Treatment choices will be further wider and conclusively select herbs that fitting the consumers' preference.

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Section: Therapeutic Agents For Alopeciamentioning

confidence: 99%