Stem Cell Research: A New Era for Reconstructive Surgery

Li, Qingfeng; Yang, Mei

doi:10.5772/31000

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Angiogenesis and Neovascularization1

Endothelial Progenitor Cells1

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2013

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Cited by 1 publication

(2 citation statements)

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“…Angiogenesis refers to the sprouting of microvessels through a preexisting capillary network, whereas neovascularization refers to vascular formation from endothelial progenitor cells that differentiate or endothelial cells that proliferate in situ [29]. Not only do they provide nutrition and oxygen for wound healing, but also they bring inflammatory cells and circulating stem cells into the wound site.…”

Section: Angiogenesis and Neovascularizationmentioning

confidence: 99%

“…Besides their paracrine secretory effect, EPCs also have potential to differentiate into endothelial cells. Moreover, in some studies of ischemic injury, EPCs were found to migrate to the ischemic area from peripheral blood and even bone marrow [29, 55]. The clinical application of EPCs also experiences similar problem as MSCs [52].…”

Section: Endothelial Progenitor Cellsmentioning

confidence: 99%

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Stem Cell Therapy for Lower Extremity Diabetic Ulcers: Where Do We Stand?

Yang

Sheng

Zhang

et al. 2013

BioMed Research International

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The impairment of wound healing in diabetic patients is an important clinical problem affecting millions of patients worldwide. Various clinical and basic science studies show that stem cell therapy, as a regenerative medical therapy, can be a good solution. In this paper, we begin with an introduction of the cellular mechanism of the diabetic ulcer. We will then discuss the advantages and limitations of various stem cell therapies that have been under extensive recent study.

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Section: Angiogenesis and Neovascularizationmentioning

confidence: 99%