Stem cell membrane-coated abiotic nanomaterials for biomedical applications

Progress of cell membrane-derived biomimetic nanovesicles for cancer phototherapy

“…As a natural delivery method, the greatly extended circulation and malignant cells-specific features of stem cells have generated intense interest for producing several biomimetic delivery systems. 181,182 To increase tumor targeting and extend circulation time, it is possible to encapsulate nanoparticles using natural cell membranes to meet the objective of cell imitation. 88,183 These nanoparticles acquire the overall biofunctions of actual cell membranes.…”

Platelet membrane-based biochemotactic-targeting nanoplatform combining PDT with EGFR inhibition therapy for the treatment of breast cancer

“…The targeting function and good biocompatibility of membrane biomimetic nanomaterials mainly depend on the functional proteins on the membrane, and the effective retention of the membrane proteins in the biomimetic nanomaterials is the key for them to exert their biological functions. 39 Therefore, the retention of PM in the PM@DLMSN/Ce6/Lap biomimetic nanoparticles was also investigated. As shown in Fig.…”

Cellular Membrane Components‐Mediated Cancer Immunotherapeutic Platforms

“…The extraction of membranes from nucleus‐containing cells such as cancer cells, immune cells, and stem cells is a more intricate process compared to nucleus‐free cells. [ 33 ] These cells require the removal of the nucleus before the extraction of the cell membrane could take place. To achieve this, the cells are subjected to hypotonic treatment and physical disruption techniques, which lead to the rupture of the cells.…”