Stem cell attachment to layer-by-layer assembled TiO2 nanoparticle thin films

Kommireddy, Dinesh S.; Sriram, Shashikanth M.; Lvov, Yuri; Mills, David K.

doi:10.1016/j.biomaterials.2006.03.042

Cited by 131 publications

(83 citation statements)

References 32 publications

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“…30 In contrast, the functionalization of HNT with organic groups that themselves possess biological activities, such as triazolium salts, confers an antiproliferative activity to halloysite. 25,29 The interaction of halloysite nanotubes with microscopic algae Chlorella pyrenoidosa was also investigated.…”

Section: Halloysite Biocompatibilitymentioning

confidence: 99%

Covalently modified halloysite clay nanotubes: synthesis, properties, biological and medical applications

et al. 2017

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a Halloysite (HNT) is a promising natural nanosized tubular clay mineral that has many important uses in different industrial fields. It is naturally occurring, biocompatible, and available in thousands of tons at low cost. As a consequence of a hollow cavity, HNT is mainly used as nanocontainer for the controlled release of several chemicals. Chemical modification of both surfaces (inner lumen and outer surface) is a strategy to tune the nanotube's properties. Specifically, chemical modification of HNT surfaces generates a nanoarchitecture with targeted affinity through outer surface functionalization and drug transport ability from functionalization of the nanotube lumen. The primary focus of this review is the research of modified halloysite nanotubes and their applications in biological and medical fields.

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Section: Halloysite Biocompatibilitymentioning

confidence: 99%

Covalently modified halloysite clay nanotubes: synthesis, properties, biological and medical applications

et al. 2017

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“…Increasing the number of layers in titanium dioxide thin films has been shown to increase surface roughness. Higher numbers of attached cells were observed on 4-layer titanium dioxide thin film than on a 1-layer thin film, with a faster rate of spreading on the rougher surface (Kommireddy et al, 2006). Moreover, multilayered and functionalized titanium films composed of chitosan and plasmid DNA demonstrated significant high transfection efficiency in mesenchymal stem cells ).…”

Section: Nanosurfacesmentioning

confidence: 96%

Novel Promises of Nanotechnology for Tissue Regeneration

Sadik¹

2012

Tissue Regeneration - From Basic Biology to Clinical Application

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“…For instance, taking biological cells as an example, it has been reported that osteoblasts preferentially adhere and proliferate on rough surfaces whilst fibroblasts are known to have an enhanced response on smooth surfaces [25,26]. Leading on from this, mesenchymal stem cells have been reported to have a significant sensitivity to surface roughness and topography [6,27]. It has also been shown that surface chemistry can play a significant role in the manipulation of biological cell growth [52,137,180].…”

Section: Prospectsmentioning

confidence: 99%

“…To this end, such surface engineering research will make inroads in to providing a pharmaceutical scale process for manufacturing platforms upon which cells can be grown and investigated. This is based on the fact that biological cells can discriminate against subtle variations in the surfaces properties of materials [1,25,26] and with an increased interest in the manipulation of stem cells [6,27]. With regards to microbiology, bacteria have evolved to become considerably more capable at adapting to their environmental conditions, increasing the likelihood for them to attach and form biofilms (complex 3-dimensional communities).…”

Section: Introductionmentioning

confidence: 99%

Surface Treatments to Modulate Bioadhesion: A Critical Review

Waugh¹,

Toccaceli²,

Gillett³

et al. 2016

rev adhes adhesives

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On account of the recent increase in importance of biological and microbiological adhesion in industries such as healthcare and food manufacturing many researchers are now turning to the study of materials, wettability and adhesion to develop the technology within these industries further. This is highly significant as the stem cell industry alone, for example, is currently worth £3.5 million in the United Kingdom (UK) alone. This paper reviews the current state-of-the-art techniques used for surface treatment with regards to modulating biological adhesion including laser surface treatment, plasma treatment, micro/nano printing and lithography, specifically highlighting areas of interest for further consideration by the scientific community. What is more, this review discusses the advantages and disadvantages of the current techniques enabling the assessment of the most attractive means for modulating biological adhesion, taking in to account cost effectiveness, complexity of equipment and capabilities for processing and analysis.

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Stem cell attachment to layer-by-layer assembled TiO2 nanoparticle thin films

Cited by 131 publications

References 32 publications

Covalently modified halloysite clay nanotubes: synthesis, properties, biological and medical applications

Covalently modified halloysite clay nanotubes: synthesis, properties, biological and medical applications

Novel Promises of Nanotechnology for Tissue Regeneration

Surface Treatments to Modulate Bioadhesion: A Critical Review

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