Stellenwert der selektiven Lasertrabekuloplastik (SLT)

Abstract

Worldwide, in recent years, selective laser trabeculoplasty (SLT) has developed into a very successful therapy for glaucoma. The article provides a review of the literature from PubMed and clinical experience. SLT is equally efficacious to argon laser trabeculoplasty (ALT) and to a first-line glaucoma medication. SLT can be used in most common forms of open-angle glaucoma and ocular hypertension. In contrast to ALT, SLT is repeatable and requires much less energy. SLT has been reported to be also successful in some rare forms of ocular hypertension/glaucoma. There is no negative influence of SLT to other forms of glaucoma treatment. Complications are rare and include intraocular pressure spikes, corneal scarring or corneal decompensation due to endothelial cell damage and cystoid macular edema. The potential of SLT as a first-line treatment of glaucoma is now under investigation. SLT is a low-risk procedure to treat glaucoma in a broad range of indications. Advantages of SLT include the potential to use SLT more and more as a primary treatment procedure. Therefore, SLT is now under intensive investigation worldwide.

Impact of Short-Term Topical Steroid Therapy on Selective Laser Trabeculoplasty Efficacy

“…Selective laser trabeculoplasty (SLT), used since 1998 when the first successful protocol was described, has become an established method for lowering the intraocular pressure (IOP) in the treatment of open-angle glaucoma (OAG) and ocular hypertension (OH) [1][2][3][4][5]. Multiple prospective or retrospective studies clear demonstrated the safety and efficacy of SLT in reducing the IOP in eyes with OAG or OH [6][7][8][9][10][11][12][13][14][15][16][17].…”

Comparison between 90‐degree and 360‐degree selective laser trabeculoplasty (SLT): A 2‐year follow‐up

“…Selective laser trabeculoplasty (SLT) and argon laser trabeculoplasty (ALT) have similar efficacy and safety profiles (McAlinden ). Recently, SLT has been the focus of considerable research due to its potential as a first‐line treatment (Schlote ). A meta‐analysis of the effect of SLT in terms of IOP control has found that, in most trials, 360‐degree SLT was comparable to medication and that there was no significant difference between 360‐ and 180‐degree SLT (McAlinden ).…”

Comparative study of the efficacy of selective laser trabeculoplasty as initial or adjunctive treatment for primary open-angle glaucoma

“…3,4,[7][8][9] Since 1998, when the first successful protocol of selective laser trabeculoplasty (SLT) was described, a 532-nm Q-switched frequency doubled Nd:YAG laser with a single pulse of short duration and low influence (energy/area) is used and has become an established method for lowering the IOP in the treatment of OAG and ocular hypertension (OH). [10][11][12][13][14] Multiple prospective or retrospective studies clearly demonstrated the safety and effectiveness of SLT in reducing the IOP in eyes with medically uncontrolled OAG, where SLT was used as adjunctive treatment option. [15][16][17][18][19][20][21][22][23][24][25] Some prospective studies investigated the effectiveness of SLT in reducing the IOP as initial treatment in OAG, most of them compared initial SLT with medical monotherapy with prostaglandin analogues (PGA).…”