Stellenwert der COVID-19-Impfung im Kontext von Long-COVID

Bauernfeind, Stilla; Schmidt, Bárbara

doi:10.1007/s00108-022-01368-y

Cited by 6 publications

(6 citation statements)

References 46 publications

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“…The current data and the uncertainty of some participants in this study illustrate the need for large-scale studies on the effects of COVID-19 vaccination and different vaccines on the symptomatology of long COVID [ 60 ]. Consistently, several studies indicate the preventive efficacy of full COVID-19 vaccination in reducing the risk of long COVID following breakthrough infection [ 26 , 62 , 63 , 65 ].…”

Section: Discussionmentioning

confidence: 56%

How do people with long COVID utilize COVID-19 vaccination and rehabilitation services and what are their experiences with these services? results of a qualitative study with 48 participants from Germany

Schmachtenberg,

Königs,

Roder

et al. 2024

BMC Public Health

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Background Studies estimate that at least 7.5% of adults are affected by long-term symptoms such as fatigue or cognitive impairment after the acute phase of COVID-19. COVID-19 vaccination may reduce the risk of long COVID. Rehabilitation can have a positive impact on recovery. This study aims to present the experiences of people with long COVID with COVID-19 vaccination and rehabilitation. Such research is important because perceptions of these measures can impact healthcare utilization and health status. Methods 48 adults with long COVID participated in this qualitative study, 25 of them in one-on-one interviews and 23 in focus groups. Participants were recruited via calls for participation on the websites and social media channels of two university hospitals and with the help of respondents’ networks. The conversations were audio-recorded, transcribed, and analyzed using qualitative content analysis. Subsequently, the results were compared, interpreted, and discussed by scientific literature. Results 35 study participants reported that they had received a COVID-19 vaccination and 16 of them stated that they had utilized a rehabilitation service. These participants had varying experiences with COVID-19 vaccination and rehabilitation. Nine of them stated that they developed long COVID despite vaccination before COVID-19. Ten participants reported vaccine reactions, and two participants reported severe side effects. Two participants reported persistent deterioration of their long COVID symptoms after vaccination. This led to uncertainty about the safety, benefits, and handling of COVID-19 vaccination. However, most participants perceived the vaccine as effective regarding milder COVID-19 sequelae. Four participants felt their rehabilitation was helpful and four participants felt it was unhelpful. Two persons found the combination of inpatient rehabilitation and rehabilitation sport helpful. Conclusions Several implications can be derived from this study: (1) researchers should explore the effects of COVID-19 vaccination on long COVID symptoms; (2) vaccination campaigns should be more responsive to the perspectives of people with long COVID on vaccination; (3) care planners should build rehabilitation facilities specialized in long COVID; (4) rehabilitation providers should train their professionals regarding long COVID and develop rehabilitation programs tailored to different clinical pictures. Trial registration German register for clinical trials DRKS00026007, 09 September 2021.

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Section: Discussionmentioning

confidence: 56%

How do people with long COVID utilize COVID-19 vaccination and rehabilitation services and what are their experiences with these services? results of a qualitative study with 48 participants from Germany

Schmachtenberg,

Königs,

Roder

et al. 2024

BMC Public Health

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“…The reference lists of five relevant review articles were searched as part of search verification [ 8 – 10 , 15 , 16 ]. This process yielded two studies that were subsequently included within the screening process [ 17 , 18 ].…”

Section: Methodsmentioning

confidence: 99%

A systematic review of the evidence on the associations and safety of COVID-19 vaccination and post COVID-19 condition

Jennings,

Corrin,

Waddell

2023

Epidemiol. Infect.

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Post COVID-19 condition (PCC) refers to persistent or recurring symptoms (>8 weeks) occurring ≤12 weeks following acute COVID-19. The objective of this systematic review was to assess the evidence on the risk of PCC with vaccination before or after COVID-19 or after developing PCC, and the safety of vaccination among those already experiencing PCC. A search was conducted up to 13 December 2022 and standard systematic review methodology was followed. Thirty-one observational studies were included. There is moderate confidence that two doses of vaccine given pre-infection reduced the odds of PCC (pooled OR (pOR) 0.67, 95% CI 0.60-0.74, I2 = 59.9%), but low confidence that one dose may not reduce the odds (pOR 0.64, 95% CI 0.31#x2013;1.31, I2 = 99.2%), and the evidence is very uncertain about the effect of three doses (pOR 0.45, 95% CI 0.10#x2013;1.99, I2 = 30.9%). One of three studies suggested vaccination shortly after COVID-19 may offer additional protection from developing PCC compared to unvaccinated individuals, but this evidence was very uncertain. For those with PCC, vaccination was not associated with worsening PCC symptoms (10 studies) and appears safe (3 studies), but it is unclear if vaccination may change established PCC symptoms.

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“…Bauernfeind und Schmidt konnten in ihrer Arbeit zum Thema Impfung gegen SARS-CoV-2 bei Patienten mit Long Covid herausfinden, dass gerade bei Durchbruchinfektionen (vollständig) geimpfte Personen vermutlich ein geringeres Risiko haben, an Long Covid zu erkranken. Die Autoren erklären weiterhin bezüglich einer Impfung als therapeutische Option: „Ein zusätzlicher therapeutischer Nutzen bei bestehendem Long Covid ist bislang ungeklärt“ 8 . Impfungen und Hygienemaßnahmen spielen somit weiterhin eine große Rolle zur Eingrenzung der Infektion mit Covid-19 und damit des Long Covid.…”

Section: Therapieunclassified

“…des Mund-Nasen-Schutzes gemäß den aktuellen Empfehlungen des Gesundheitsministeriums und RKI.Bauernfeind und Schmidt konnten in ihrer Arbeit zum Thema Impfung gegen SARS-CoV-2 bei Patienten mit Long Covid herausfinden, dass gerade bei Durchbruchinfektionen (vollständig) geimpfte Personen vermutlich ein geringeres Risiko haben, an Long Covid zu erkranken. Die Autoren erklären weiterhin bezüglich einer Impfung als therapeutische Option: "Ein zusätzlicher therapeutischer Nutzen bei bestehendem Long Covid ist bislang ungeklärt"[8]. Impfungen und Hygienemaßnahmen spielen somit weiterhin eine große Rolle zur Eingrenzung der Infektion mit Covid-19 und damit des Long Covid.In der PraxisDer Hausarzt ist für Betroffene meist erster Ansprechpartner und koordiniert die Versorgung im ambulanten Rahmen im Sinne eines interdisziplinären Managements durch Vernetzung mit verschieden Fachdisziplinen.…”

unclassified

Aktueller Stand Long Covid

Grabmann¹

2022

Erfahrungsheilkunde

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ZusammenfassungZu Beginn der Covid-19-Pandemie war es die akute Infektion, die im Fokus des Interesses lag, doch der Blickwinkel hat sich geändert. Nach der Infektion können bei den Betroffenen Beeinträchtigungen sowohl auf körperlicher als auch auf geistiger Ebene bestehen bleiben – das sog. „Long-Covid-Syndrom“ oder „Post-Covid-Syndrom“. Das Gesundheitswesen forscht zu Ursachen und Therapiemöglichkeiten. In der Praxis hat sich gezeigt, dass bisher gut etablierte naturheilkundliche Verfahren einen positiven Beitrag zur Therapie von Patienten mit Long Covid leisten. Gerade die Kombination von Schulmedizin und Naturheilkunde im Sinne eines integrativen Therapieansatzes kann ein breites Spektrum zielgerichteter Behandlungsmaßnahmen bieten, die dem Ausmaß der von Patienten als zum Teil sehr belastend empfundenen Folgen der Covid-19-Infektion mit seiner Bandbreite an Symptomen gerecht werden könnte.

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Stellenwert der COVID-19-Impfung im Kontext von Long-COVID

Cited by 6 publications

References 46 publications

How do people with long COVID utilize COVID-19 vaccination and rehabilitation services and what are their experiences with these services? results of a qualitative study with 48 participants from Germany

How do people with long COVID utilize COVID-19 vaccination and rehabilitation services and what are their experiences with these services? results of a qualitative study with 48 participants from Germany

A systematic review of the evidence on the associations and safety of COVID-19 vaccination and post COVID-19 condition

Aktueller Stand Long Covid

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