Stellate nonhereditary idiopathic foveomacular retinoschisis concomitant to exudative maculopathies

Casalino, Giuseppe; Upendran, M; Bandello, Francesco; Chakravarthy, Usha

doi:10.1038/eye.2016.17

Cited by 12 publications

(12 citation statements)

References 2 publications

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“…In 2016, Casalino et al 12 reported two cases of SNIFR in patients with concomitant neovascular agerelated macular degeneration; but to our knowledge, our case report is the first record of a patient with unilateral SNIFR in a patient with MacTel Type 2.…”

Section: Discussionmentioning

confidence: 67%

Stellate Nonhereditary Idiopathic Foveomacular Retinoschisis in a Patient With Macular Telangiectasia Type 2

Falb¹,

Malle²,

Haas³

et al. 2021

RETINAL Cases &Amp; Brief Reports

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Purpose: To present a case of unilateral stellate nonhereditary idiopathic foveomacular retinoschisis in a patient with macular telangiectasia (MacTel) Type 2.Methods: Single-patient case report.Results: A 61-year-old female white patient was referred to our clinic with metamorphopsia and reduction of visual acuity over a period of 2 months on her right eye. Ocular findings in her right eye included reduced best-corrected visual acuity of 20/ 63 Snellen, foveomacular retinoschisis with extension to the lower middle periphery, central elevation of the neurosensory retina, and macular telangiectasia (MacTel) Type 2. Other causes of foveomacular retinoschisis, such as glaucoma, myopic degeneration, optic or scleral pit, X-linked juvenile retinoschisis, degenerative retinoschisis, and vitreomacular traction, were ruled out. The patient had no history of niacin or taxane medication, which may cause rather similar appearing cases of cystoid macular edema without leakage in fluorescein angiography. Because of the unilateral presentation, uneventful medical history, female sex, and the absence of known hereditary diseases or retinal pathologies in the patient's family history, hereditary predisposition appears to be highly unlikely.Conclusion: To our knowledge, this is the first reported case of stellate nonhereditary idiopathic foveomacular retinoschisis in combination with MacTel Type 2. Whether or not MacTel Type 2 plays a role in the development of stellate nonhereditary idiopathic foveomacular retinoschisis or has an impact on its clinical course requires further investigation. Furthermore, we suggest a significant involvement of Henle fiber layer in the process of intraretinal expansion in optical coherence tomography, in accordance with the most recent published nomenclature.

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Section: Discussionmentioning

confidence: 67%

Stellate Nonhereditary Idiopathic Foveomacular Retinoschisis in a Patient With Macular Telangiectasia Type 2

Falb¹,

Malle²,

Haas³

et al. 2021

RETINAL Cases &Amp; Brief Reports

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“…FFA showed no leakage, but the symptomatic patient presented faint hyperfluorescence on the fovea, suggesting a subtle retinal pigment epithelial abnormality. None of the three subjects could perceive entopic phenomena (Haidingerʼs brushes and Maxwellʼs spot), which was Casalino et al reported two female patients with SNIFR associated with neovascular age-related macular degeneration (AMD), suggesting that multimodal imaging is necessary to detect SFR, which might be diagnosed as intraretinal fluid and lead to unnecessary treatment [13]. Ajlan and Hammanji recently published a case of SNIFR in a 27-year-old male patient who developed visual symptoms (reduced vision 20/40 from 20/20) in the affected eye and was treated successfully with topical dorzolamide hydrochloride 2 % (pa-tientʼs vision was restored back to 20/20 with simultaneous anatomical improvement) [14].…”

Section: Discussionmentioning

confidence: 93%

Stellate Nonhereditary Idiopathic Foveomacular Retinoschisis in a Female Patient: Case Report and Brief Literature Review

Panos

Zambarakji

Mckechnie

et al. 2020

Klin Monatsbl Augenheilkd

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“…In the absence of other structural change, average visual acuity ranges from 20/20 to 20/30 [1,2 ▪▪ ]. In the rare cases of vision worse than 20/50, other factors such as subretinal fluid or exudative maculopathy are usually seen [1,7]. SNIFR can present unilaterally or bilaterally, but the preponderance of cases appears to be unilateral [1,2 ▪▪ ,8].…”

Section: Clinical and Imaging Characteristics Of Stellate Nonheredita...mentioning

confidence: 99%

“…At its core, SNIFR results from the development of cystic spaces at the level of the HFL and outer plexiform layer (OPL) [1,9]. Nonleakage on fluorescein angiography and resistance to anti-VEGF therapy support that these cavities are unlikely to be an exudative maculopathy [7]. Instead, recent reports have shown compelling evidence that vitreomacular forces may play a role in schisis development.…”

Section: Pathophysiology Of Stellate Nonhereditary Idiopathic Foveoma...mentioning

confidence: 99%

Stellate nonhereditary idiopathic foveomacular retinoschisis and an approach to the differential diagnosis of macular star

Light

Pyfer

Salabati

et al. 2022

Current Opinion in Ophthalmology

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Purpose of reviewThis review aims to introduce stellate nonhereditary idiopathic foveomacular retinoschisis (SNIFR) and its differential diagnosis. We summarize findings from case reports and series published in the last few years on the clinical and imaging findings in SNIFR. Recent findingsSNIFR presents as either a unilateral or bilateral macular star on fundus examination without clinical or imaging evidence of exudation or frank vitreomacular traction. optical coherence tomography (OCT) imaging shows schisis cavities in the Henle fibre and outer plexiform layers that correspond to the stellate en face findings. Visual acuity is usually minimally affected, and the presence of significant vision loss should prompt high clinical suspicion for alternate diagnoses. SummarySNIFR is a recently characterized clinical entity that serves as an important addition to the differential diagnosis of a macular star. It is a diagnosis of exclusion and should be distinguished from other causes of macular star such as neuroretinitis, vitreomacular traction, ocular manifestations of malignant hypertension, congenital juvenile X-linked macular schisis, myopic maculopathy, optic pit maculopathy, nicotinic acid maculopathy or taxane maculopathy among others.

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Stellate nonhereditary idiopathic foveomacular retinoschisis concomitant to exudative maculopathies

Cited by 12 publications

References 2 publications

Stellate Nonhereditary Idiopathic Foveomacular Retinoschisis in a Patient With Macular Telangiectasia Type 2

Stellate Nonhereditary Idiopathic Foveomacular Retinoschisis in a Patient With Macular Telangiectasia Type 2

Stellate Nonhereditary Idiopathic Foveomacular Retinoschisis in a Female Patient: Case Report and Brief Literature Review

Stellate nonhereditary idiopathic foveomacular retinoschisis and an approach to the differential diagnosis of macular star

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