Stearoylamido‐D‐Glucamine Hydrogelators for Thixotropic Molecular Gels with Tunable Softness by Chemical Modification

Abstract

Low-molecular-weight hydrogelators containing stearoyl, glycine, and D-glucamine moieties with or without methyl groups were synthesized to prepare chemically tuned molecular hydrogels. To evaluate the role of hydrogen bonding of hydrogelators in molecular hydrogel formation, the author has newly synthesized hydrogelators with or without methyl groups at their NÀ H in amide groups, contributing to the hydrogen bond formation in fiber in molecular hydrogels. The obtained hydrogels exhibited improved thixotropic performance with tunable softness, exhibiting pseudo-reversible thixotropic cycles that depended on the methyl substitution positions in the hydrogelators. To change the hydrogen bonds' positions by chemical modification has made it possible to tune the mechanical properties of molecular gels.

Synthetic approaches of carbohydrate based self-assembling systems

“…Four D-glucamine derivatives containing stearoyl and glycine groups were synthesized and analyzed. 53 As shown in Fig. 8, these glucamides 99a-d were able to form hydrogels effectively.…”

Characterization and Fabrication of Xerogel Polymeric Nanocomposites and Multifunctional Applications

“…XG is a porous, architectured material emanating from varying drying strategies of wet gels . Thus, the enchanting and peculiar attributes of these porous materials are garnered from the peculiar exibility as well as resilience of the sol-gel fabrication procedure, garnered in synergy with either ambient drying (X-G) or supercritically a liated drying (A-G) [81][82][83][84][85][86][87][88][89][90][91][92][93][94][95][96][97][98][99][100]. As already elucidated, these substrates have been fabricated from varying precursors, like carbon, silica, and biopolymeric entities and possessing differing biological, physical, chemical, and mechanical, attributes, relative to varying parameters, including precursoral substrates, solvent medium, as well as drying parameters [101][102][103][104][105][106][107][108][109][110][111][112][113][114][115][116][117][118][119][120].…”