Steady-State Visual Evoked Potentials and Phase Synchronization in Migraine Patients

Angelini, L.; Tommaso, Marina de; Guido, Marco; Hu, Kun; Ivanov, Plamen Ch.; Marinazzo, Daniele; Nardulli, G.; Nitti, L.; Pellicoro, M.; Pierro, Cinzia; Stramaglia, Sebastiano

doi:10.1103/physrevlett.93.038103

Cited by 102 publications

(82 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…16 By contrast, in patients who have migraine without aura, the alpha rhythm remains highly synchronized across different brain areas during visual stimulation. 17 This pattern does not depend on the alpha amplitude, but pertains to the synchrony of temporal activation and dynamic interactions (such as functional connectiv ity) between brain areas, 18 and to their modification by sensory stimuli. Some researchers have suggested that functional connectivity is determined by both cortico cortical and thalamocortical loops.…”

Section: Increased Synchronizationmentioning

confidence: 97%

“…The results have provided three main sets of observations, which were consistent across most studies. First, between attacks, a stimulus frequency dependent increase occurs in photic driving and synchronization of EEG alpha (8-13 Hz) and beta (13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24)(25)(26)(27)(28)(29)(30) rhythms. Second, the interictal migrain ous brain is characterized by a habituation (or adapta tion) deficit of cortical evoked responses to repetitive, non noxious sensory stimuli-this deficit normalizes during an attack.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Altered processing of sensory stimuli in patients with migraine

et al. 2014

View full text Add to dashboard Cite

| Migraine is a cyclic disorder, in which functional and morphological brain changes fluctuate over time, culminating periodically in an attack. In the migrainous brain, temporal processing of external stimuli and sequential recruitment of neuronal networks are often dysfunctional. These changes reflect complex CNS dysfunction patterns. Assessment of multimodal evoked potentials and nociceptive reflex responses can reveal altered patterns of the brain's electrophysiological activity, thereby aiding our understanding of the pathophysiology of migraine. In this Review, we summarize the most important findings on temporal processing of evoked and reflex responses in migraine. Considering these data, we propose that thalamocortical dysrhythmia may be responsible for the altered synchronicity in migraine. To test this hypothesis in future research, electrophysiological recordings should be combined with neuroimaging studies so that the temporal patterns of sensory processing in patients with migraine can be correlated with the accompanying anatomical and functional changes.

show abstract

Section: Increased Synchronizationmentioning

confidence: 97%

Section: Introductionmentioning

confidence: 99%

Altered processing of sensory stimuli in patients with migraine

et al. 2014

View full text Add to dashboard Cite

show abstract

“…This leads us to the phase reduction theory of weakly coupled nonlinear oscillators [6], which states that a weak interaction is sufficient to synchronize the limit cycle oscillators if their natural frequencies are close enough to each other. Because of its simplicity, the theory of phase oscillators has been applied to a wide variety of systems such as electrochemical oscillators [13], neurons [14], brain activity [15,16], genetic networks [17], and circadian oscillations [18,19]. This type of synchronization, however, has not yet been extensively investigated in the field of mechanical engines.…”

Section: Introductionmentioning

confidence: 99%

Synchronization of coupled Stirling engines

Kada

Hojyo

Tokuda

2014

NOLTA

View full text Add to dashboard Cite

Abstract:Because of an increasing demand on electric power and limited resources for conventional fuels, highly efficient engine that is capable of converting energy resource to electric power with a small loss is awaited. In this respect, Stirling engine provides a strong potential because of its efficient thermodynamic cycle, which is ideally close to the theoretical limit of the Carnot cycle. Practical use of the Stirling engine, however, has been limited because of its low output power. Towards its wider applicability, simultaneous operation of many individual Stirling engines is indispensable to increase the output power. This paper presents an experimental study of synchronized dynamics of two coupled Stirling engines. It is shown that the synchronized operation of the population of engines provides a key technology to extend the system size so as to produce a large-scale electric energy.

show abstract

“…Specifically, studies have found coupling between the cardiac rhythm and other systems: phase synchronization was observed between the heartbeat and respiration during normal conditions [61] and during respiratory sinus arrhythmia [62,63], change of cardiorespiratory phase synchronization with newborns' age [64], and with the level of anaesthesia [65]. Phase analysis methods have been used to probe spatial synchronization of oscillations in blood distribution systems [66], between cortical centers during migraine [67], as well as between certain brain areas and muscle activity of the limbs [68].…”

Section: Introductionmentioning

confidence: 99%

Cross-correlation of instantaneous phase increments in pressure-flow fluctuations: Applications to cerebral autoregulation

Chen

Stanley

et al. 2006

Phys. Rev. E

View full text Add to dashboard Cite

We investigate the relationship between the blood flow velocities (BFV) in the middle cerebral arteries and beat-to-beat blood pressure (BP) recorded from a finger in healthy and post-stroke subjects during the quasisteady state after perturbation for four different physiologic conditions: supine rest, head-up tilt, hyperventilation, and CO 2 rebreathing in upright position. To evaluate whether instantaneous BP changes in the steady state are coupled with instantaneous changes in the BFV, we compare dynamical patterns in the instantaneous phases of these signals, obtained from the Hilbert transform, as a function of time. We find that in post-stroke subjects the instantaneous phase increments of BP and BFV exhibit well-pronounced patterns that remain stable in time for all four physiologic conditions, while in healthy subjects these patterns are different, less pronounced, and more variable. We propose an approach based on the cross-correlation of the instantaneous phase increments to quantify the coupling between BP and BFV signals. We find that the maximum correlation strength is different for the two groups and for the different conditions. For healthy subjects the amplitude of the cross-correlation between the instantaneous phase increments of BP and BFV is small and attenuates within 3−5 heartbeats. In contrast, for post-stroke subjects, this amplitude is significantly larger and cross-correlations persist up to 20 heartbeats. Further, we show that the instantaneous phase increments of BP and BFV are cross-correlated even within a single heartbeat cycle. We compare the results of our approach with three complementary methods: direct BP-BFV cross-correlation, transfer function analysis, and phase synchronization analysis. Our findings provide insight into the mechanism of cerebral vascular control in healthy subjects, suggesting that this control mechanism may involve rapid adjustments (within a heartbeat) of the cerebral vessels, so that BFV remains steady in response to changes in peripheral BP.

show abstract

Steady-State Visual Evoked Potentials and Phase Synchronization in Migraine Patients

Cited by 102 publications

References 18 publications

Altered processing of sensory stimuli in patients with migraine

Altered processing of sensory stimuli in patients with migraine

Synchronization of coupled Stirling engines

Cross-correlation of instantaneous phase increments in pressure-flow fluctuations: Applications to cerebral autoregulation

Contact Info

Product

Resources

About