Status of oxidative stress, trace elements, sialic acid and cholinesterase activity in cattle naturally infected with Babesia bigemina

Esmaeilnejad, Bijan; Tavassoli, Mousa; Dalir‐Naghadeh, Bahram; Samiei, Awat; Rajabi, Sepideh; Mohammadi, Vahid; Anassori, Ehsan; Ehteshamfar, Shahin

doi:10.1016/j.cimid.2020.101503

Cited by 13 publications

(6 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This is supported by a significant reduction in the level of the antioxidants GSH and CAT in buffaloes of group I and II compared to haemo-parasite negative buffaloes of group III (Table 5). Oxidative stress in cattle infected with tick-borne pathogens has been extensively reported worldwide which is in concurrence with our observations (AL-Hosary, et al 2015;Esmaeilnejad et al 2020). Similarly, in buffaloes, oxidative stress and parasitic burden-dependent oxidative damages to erythrocytes by T. annulata infection in buffaloes have been reported (Molayi-Jabdaragi et al 2020).…”

Section: Oxidative Stress and Biochemical Responsesupporting

confidence: 92%

Mixed Infection of Tick-borne Haemo-parasites in Water Buffalo and Associated Pathological Responses and Treatment

Kumar¹,

Kumar²,

Roy³

et al. 2021

IJAR

View full text Add to dashboard Cite

Background: Water buffaloes are important milch species of tropical and subtropical countries. In general, they are considered to more resistant to diseases compared to crossbred cattle. However, a recent problem of tick-borne diseases in the water buffaloes by the field veterinarians and farmers causing production losses was observed. The study was conducted to explore the spectrum of tick-borne diseases (TBDs) infections in buffaloes and analyze the associated risk factors. Methods: Acute-phase response, cytokine and oxidative stress in infected buffaloes with TBDs were evaluated and compared with the negative buffaloes (control) to elucidate their role in pathogenesis and outcome of infection. The study was undertaken in 107 tick-infested water buffaloes. The conventional Giemsa stained blood smear (GSBS) based confirmation and classification of infection of haemo-parasites were made. The statistical model was used to understand their relevance with TBDs. Conclusion: Tick-borne disease in water buffaloes must be looked upon seriously to maintain good productivity. The buffaloes are often accompanied by low and un-yielding clinical symptoms due to associated co-infections of haemo-parasites. Our study showed that the buffaloes had a high prevalence (47.66%) of haemo-parasites transmitted by the ticks associated with co-infections and a low level of parasitemia. Most buffaloes responded symptomatically with the different modalities administered. Production parameter was not restored post 15 days of treatment. Oxidative stress is one of the important mechanisms of production losses in infected buffaloes.

show abstract

Section: Oxidative Stress and Biochemical Responsesupporting

confidence: 92%

Mixed Infection of Tick-borne Haemo-parasites in Water Buffalo and Associated Pathological Responses and Treatment

Kumar¹,

Kumar²,

Roy³

et al. 2021

IJAR

View full text Add to dashboard Cite

show abstract

“…Similar Plus minus findings were also reported by several workers in cattle suffering from cerebral babesiosis. In case of B.bigemina, mild form of anemia has been reported by various workers (Vikrant et al, 2013) but in present study sever form of anemia has been reported might be due to high level of parasitaemia which leads to oxidative damage to the erythrocytes (Saleh, 2009) or suppression of erythropoiesis and phagocytosis of non infected erythrocyte due to changing in its antigenic surface (Esmaeilnejad et al, 2020). Haemoglobinuria was present in early stage of infection but urine was transparent in latter stage of infection which is in corroborated with findings of Bock, 2004. The morphology of parasite in blood smear examination revealed that the present case is of B. bigemina and this was again confirmed by molecular method.…”

Section: Resultsmentioning

confidence: 48%

First Report on Molecular Identification of Babesia bigemina in a Nervous Signs Evident Naturally Infected Holstein-Friesian Cattle from Central India

Agrawal

Das

Jaiswal

et al. 2021

IJAR

View full text Add to dashboard Cite

Background: Bovine babesiosis caused by an intraerythrocytic apicomplexan protozoon responsible for the most prevalent and costly tick borne diseases (TBD’s) of cattle throughout the globe. Cerebral babesiosis of bovine is fatal and mainly caused by Babesia bovis. To the knowledge of author, there is no confirm molecular report of Babeisa bigemina caused cerebral babesiosis in cattle. Therefore, authors want to report Babesia bigemina caused cerebral babesiosis on record. Methods: In the year 2015, a Holstein-Friesian cow aged 3 years and weighing approximately 300 kg, was attended at Jabalpur, (M.P.) with the clinical signs of high rise in temperature (104°F), recumbency, severe dysponea, peculiar sound during open mouth breathing, pale color of eye conjunctiva and mucous membrane of vagina, convulsions, sever anaemia, paddling of legs at frequent interval. After preparation of peripheral thin blood smear from animal at the site of collection and fixation with methanol, blood sample brought to Department of Veterinary Parasitology, College of Veterinary Science and A.H, Jabalpur and stained by standard protocol for Giemsa staining. Genomic DNA was isolated from the collected blood sample using QIAamp® DNA blood mini kit following the manufacturer’s recommendations and PCR was performed. Conclusion: The thin blood smear examination revealed the presence of Babesia parasite. The species of Babesia was confirmed by molecular amplification of genomic DNA as B. bigemina. This might be the first confirmed report of cerebral babesiosis caused by B. bigemina from Central India.

show abstract

“…In contrast to this, in anaemic cattle infected with B. bigemina decreased serum levels of copper, zinc, manganese and selenium along with increased levels of iron were observed. It can be assumed that the decreased levels of trace elements (including Mn) represent their co-ordinated antioxidant role along with antioxidant enzyme activities during the infection (Esmaeilnejad et al, 2020).…”

Section: Discussionmentioning

confidence: 99%

Elevated serum manganese concentration in dogs as a possible predisposing factor of cerebral babesiosis in dogs

Teodorowski¹,

Adaszek

et al. 2021

Acta Veterinaria Hungarica

View full text Add to dashboard Cite

The aim of this study was to demonstrate a relationship between the occurrence of clinical signs of brain involvement in dogs with babesiosis and the concentration of manganese (Mn) in their serum. The study included seven dogs with early babesiosis (Group 1), seven dogs with cerebral babesiosis (Group 2) and seven healthy dogs (Group 3). Haematological and biochemical blood tests were performed in all dogs, and the results were analysed statistically. The Mann–Whitney rank test was used to demonstrate the differences in Mn concentrations, as well as other haematological and biochemical parameters between groups. In dogs in Group 2 with cerebral babesiosis, as compared to dogs in Groups 1 and 3, a statistically significant increase in serum Mn concentration was shown (P = 0.002 and P = 0.029) that may have been associated with the development of anaemia and/or impairment of liver function. Given the well-established neurotoxic effects of Mn in humans, experimental rodents and primates, additional studies on the role of Mn in the pathogenesis of the cerebral form of canine babesiosis are warranted.

show abstract

Status of oxidative stress, trace elements, sialic acid and cholinesterase activity in cattle naturally infected with Babesia bigemina

Cited by 13 publications

References 29 publications

Mixed Infection of Tick-borne Haemo-parasites in Water Buffalo and Associated Pathological Responses and Treatment

Mixed Infection of Tick-borne Haemo-parasites in Water Buffalo and Associated Pathological Responses and Treatment

First Report on Molecular Identification of Babesia bigemina in a Nervous Signs Evident Naturally Infected Holstein-Friesian Cattle from Central India

Elevated serum manganese concentration in dogs as a possible predisposing factor of cerebral babesiosis in dogs

Contact Info

Product

Resources

About