1979
DOI: 10.1177/0310057x7900700107
|View full text |Cite
|
Sign up to set email alerts
|

Status Epilepticus Controlled by Althesin Infusion

Abstract: Althesin will control status epilepticus when other agents jail. Its major advantage over other agents is its lack of accumulation because it is readily metabolized. Three patients are reported and relevant literature is discussed.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3

Citation Types

0
5
0

Year Published

1979
1979
2014
2014

Publication Types

Select...
8
1

Relationship

0
9

Authors

Journals

citations
Cited by 15 publications
(5 citation statements)
references
References 8 publications
0
5
0
Order By: Relevance
“…Concern has been expressed in the literature that Althesin may cause convulsions or may facilitate an epileptic focus (Uppington 1973) in a manner similar to methohexitone (Howells 1968). However, Chin, Havill and Rothwell ( 1979) has reported the use of AIthesin in refractory status epilepticus and we have also reported success in a similar case (Saady, Wong and Hicks 1979).…”
Section: Discussionmentioning
confidence: 55%
“…Concern has been expressed in the literature that Althesin may cause convulsions or may facilitate an epileptic focus (Uppington 1973) in a manner similar to methohexitone (Howells 1968). However, Chin, Havill and Rothwell ( 1979) has reported the use of AIthesin in refractory status epilepticus and we have also reported success in a similar case (Saady, Wong and Hicks 1979).…”
Section: Discussionmentioning
confidence: 55%
“…It is possible that the drug intensifies EEG abnormalities in patients suffering from epilepsy, in common with other anaesthetic agents in subnarcotic doses. For example, Althesin causes appearance of bitemporal abnormalities in EEG tracings of epileptic patients [18] but nevertheless has powerful anticonvulsant activity in experimental epilepsy and in epileptic status [4,5].…”
Section: Discussionmentioning
confidence: 99%
“…Several years ago, Althesin was used successfully in patients suffering from status epilepticus where benzodiazepines, clonazepam and thiopentone had failed [3][4][5]. Unfortunately, this anaesthetic agent is no longer available, but its success suggests that other i.v.…”
mentioning
confidence: 99%
“…Alphaxalone has been reported to be a more efficacious agent in treatment of intractable status epilepticus than classic GABAergic agents like barbiturates (Chin et al, 1979). It is also more effective in suppressing epileptic activity in experimental models than thiopental and diazepam (DeRiu et al, 1987).…”
Section: Discussionmentioning
confidence: 99%