Status and perspectives of biomarker validation for diagnosis, stratification, and treatment

Skov, Jane; Kristiansen, Karsten; Jespersen, Jørgen; Olesen, Pia

doi:10.1016/j.puhe.2020.11.002

Cited by 3 publications

(4 citation statements)

References 6 publications

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“…Biomarkers may offer diagnostic utility when they are easily measured, and the disease is not. 3 This is rarely the case for skin conditions. Facial redness in rosacea may be easier to measure and quantify through clinical diagnosis than analysis of the presumed biomarkers.…”

mentioning

confidence: 99%

“…The clinical benefit of biomarkers for rosacea (or other cutaneous skin diseases traditionally measured visually) is not supported based on the evidence available. 1,3 The conclusion that there is potential for biomarkers to aid in diagnosis and support therapeutic development for rosacea cannot yet be made.…”

mentioning

confidence: 99%

“…Biomarkers may offer diagnostic utility when they are easily measured, and the disease is not 3 . This is rarely the case for skin conditions.…”

mentioning

confidence: 99%

“…Though there may be some scientific value in assessing biomarker levels for rosacea, it is not clear what that is since association does not indicate causality. The clinical benefit of biomarkers for rosacea (or other cutaneous skin diseases traditionally measured visually) is not supported based on the evidence available 1,3 . The conclusion that there is potential for biomarkers to aid in diagnosis and support therapeutic development for rosacea cannot yet be made.…”

mentioning

confidence: 99%

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